Tag: progesterone

1. Women with early pregnancy bleeding administered progesterone experienced similar rates of live births occurring after 34 weeks’ gestation as women treated with placebo. 2. Subgroup analysis was generally inconclusive, though many subgroups had risk ratios approaching significance supporting progesterone use. Evidence Rating Level: 1 (Excellent)   Study Rundown: Miscarriages are not uncommon in...
1. Women with early pregnancy bleeding administered progesterone experienced similar rates of live births occurring after 34 weeks’ gestation as women treated with placebo. 2. Subgroup analysis was generally inconclusive, though many subgroups had risk ratios approaching significance supporting progesterone use. Evidence Rating Level: 1 (Excellent)   Study Rundown: Miscarriages are not uncommon...
1. Women with a history of unexplained recurrent miscarriages who were treated with vaginal progesterone during the first trimester did not have a significant difference in rate of live births compared to those who received placebo. 2. There were no differences in terms of neonatal outcomes or anomalies between the...
1. Among women taking 17 hydroxyprogesterone caproate (progesterone) injections, only those with BMI ≤30 kg/m2 were less likely to experience preterm birth. 2. Progesterone injections were associated with a decreased risk of preterm birth among women weighing ≤165 lbs. Evidence Rating Level: 2 (Good)            Study Rundown: PTB complicates over 11% of deliveries...
1. Women randomized to the treatment with progesterone (17-OHP-C) had a similar incidence of preterm birth compared with women in the control group. 2. The treatment and control groups demonstrated no differences in incidence of maternal or neonatal complications. Evidence Rating Level: 1 (Excellent) Study Rundown: In the U.S., over...
Classics Series, Landmark Trials in Medicine
1. In women with a history of preterm birth, weekly progesterone injections reduced the risk of delivery prior to 37, 35, and 32 weeks gestation. 2. Number needed to treat to prevent one preterm birth <37 weeks was six women. Original date of publication: June 2003 Study Rundown: Spontaneous preterm birth is...
Feb 16th – A 3-day course of progesterone therapy was effective in treating abnormal uterine bleeding (AUB). Image: PD 1. A 3-day course of progesterone therapy was effective in treating abnormal uterine bleeding (AUB). 2. This treatment regimen resulted in the cessation of bleeding within 5 days. This pilot clinical trial found that...