Two scores for risk stratification of adults presenting with syncope may be effective at identifying those with low risk
1. The Canadian Syncope Risk Score (CSRS) and FAINT score are effective at identifying which adult patients presenting to the...
Neurology
Reports of high-impact neurology studies by medical professionals
Intra-arterial alteplase after thrombectomy improves three-month functional recovery in large vessel stroke
1. Adding a thrombolytic agent delivered through the arterial catheter immediately following mechanical clot extraction increased near-complete functional recovery at...
Thrombectomy may improve functional independence in acute ischemic stroke with medium vessel occlusion
1. In this randomized controlled trial, acute stroke patients with medium-vessel occlusion and moderate-to-severe neurological deficits who received thrombectomy in...
Physical frailty is associated with increased risk of epilepsy
1. Physical frailty, particularly slow gait speed, was independently associated with a significantly increased risk of incident epilepsy in a...
A multimodal approach combining cognitive assessment with biomarkers may accurately predict dementia risk
1. Plasma p-tau217 was the strongest individual biomarker for predicting progression to Alzheimer's disease dementia in patients with subjective cognitive...
A non-invasive neurostimulation intervention may improve social communication impairment in children with autism spectrum disorder
1. Five days of accelerated continuous theta burst stimulation (a-cTBS) targeting the left primary motor cortex improved social communication impairment...
Calcitonin gene-related peptide therapies effective for chronic migraine
1. In this systematic review and meta-analysis, prophylaxis with calcitonin gene-related peptide-targeting therapies (eptinezumab, erenumab, fremanezumab, galcanezumab, and atogepant) consistently...
Triple low-dose antihypertensive pill reduced recurrent stroke after intracerebral hemorrhage
1. In clinically stable patients with prior intracerebral hemorrhage, a fixed-dose combination pill containing three low-dose antihypertensive agents reduced recurrent...
Tenecteplase (TNKase) may worsen functional outcomes in older patients with minor ischemic stroke
1. Tenecteplase (TNKase) improved early recanalization and short-term neurologic recovery, but in patients older than 80 years with minor ischemic...
Transcranial ultrasound stimulation may modulate acute heat pain perception
1. Primary somatosensory cortex stimulation lowered heat pain threshold and heat pain tolerance in the contralateral hand. 2. Both primary...
