Vitamin D supplementation is not preventative for statin-associated muscle symptoms or statin discontinuation
1. A randomized controlled trial found that pretreatment with supplemental vitamin D did not reduce the risk of statin-associated muscle...
Poor pregnancy outcomes including placental pathologies associated with amniotic fluid embolism and contribute to maternal mortality
1. A large, retrospective cohort study identified risk factors for amniotic fluid embolism during pregnancy, including a strong association with...
Development and validation of a prediction model to estimate ascending aorta diameter in asymptomatic individuals
1. A clinical score used to estimate the diameter of the ascending aorta was developed and validated using retrospective data...
Contemporary pattern of treatment time and in-hospital mortality among US patients with ST-segment elevation myocardial infarction between 2018-2021
1. The adjusted in-hospital mortality rate was lower for patients who received treatment within the range of target times versus...
Travel time to abortion facilities in the United States significantly increased after the Dobbs v Jackson Women’s Health Decision
1. Travel time to abortion facilities was significantly increased after the landmark trial Dobbs vs. Jackson Women’s Health in states...
Variation in prostate cancer screening rates associated with subsequent metastatic prostate cancer incidence
1. A retrospective analysis demonstrated that prostate-specific antigen (PSA) screening has overall declined in popularity in recent years. 2. Health...
Angiotensin receptor blockers may reduce the incidence of epilepsy in patients with hypertension
1. Amongst a cohort of individuals with arterial hypertension, those who were taking angiotensin receptor blocker antihypertensives had the lowest...
Beneficial effect of intensive blood pressure control on cardiovascular and all-cause mortality not persist after trial intervention – a secondary analysis of the SPRINT trial
1. Intensive blood pressure control regime was associated with improved cardiovascular and all-cause mortality at a median follow-up point of...
Cefepime/enmetazobactam superior to piperacillin/tazobactam for the treatment of complicated urinary tract infections and acute pyelonephritis
1. In this randomized controlled trial, treatment of acute pyelonephritis and complicated urinary tract infection caused by gram-negative organisms with...
Prenatal exposure to high-dose folic acid associated with increased cancer risk in children of mothers with epilepsy
1. The risk of cancer was higher amongst children of mothers with epilepsy who were exposed to high-dose folic acid...
