1. A chemical library screen identified a compound (termed altered generation of neurons, or ALGERNON) that promoted the proliferation of...
1. When three therapies that eliminate senescent cells were separately tested on aged mice, the animals demonstrated improved bone microarchitecture...
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1. In mouse models of polycystic ovarian syndrome (PCOS), elevated adiponectin levels ameliorated metabolic dysfunction. 2. However, adiponectin was unable...
1. The gene editing tool CRISPR-Cas9 was used to correct a mutant paternal MYBPC3 allele in human preimplantation embryos. 2....
1. In a mouse model of breast cancer, treatment with the chemotherapy paclitaxel (Ptx) enhanced tumor cell dissemination and the...
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1. Following treatment with metformin, mouse models of Fragile X syndrome (FXS) demonstrated restored neurological signaling activity and synaptic function....
1. Blood from liver transplant patients treated with a calcineurin inhibitor (CNI) showed increased levels of apoptotic regulatory T cells...
1. Thymosin α1 (Tα1), an immunomodulatory drug currently in use, decreased lung inflammation in a mouse model of cystic fibrosis...
1. Researchers manufactured a microfluidic biochip, using an inkjet printing system to apply conductive nanoparticles to a polymer substrate. 2....
1. A lipid nanoparticle (LNP) delivery system was developed to introduce factor IX (FIX) messenger RNA (mRNA) into a FIX...
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