Birinapant shows efficacy in clearing hepatitis B infection [PreClinical]
1. The small molecule drug birinapant promoted elimination of hepatitis B virus (HBV) in a mouse model of chronic infection....
1. The small molecule drug birinapant promoted elimination of hepatitis B virus (HBV) in a mouse model of chronic infection....
1. Researchers developed a two-part method for cutaneous influenza vaccination: a microneedle array (MNs) that delivered vaccine without causing skin...
1. A small molecule screen identified that microtubule-destabilizing (MD) drugs enhanced the cancer-killing activity of oncolytic vesicular stomatitis virus. 2....
1. Both in vitro and in a mouse model, guanabenz treatment improved the survival of myelin-producing oligodendrocyte cells in the...
1. Mucus from cystic fibrosis patients had a rope-like structure and high elasticity due to chemical cross-links between mucin proteins....
1. Tuberculosis (TB) granulomas exhibited similar properties to solid cancerous tumors, characterized as dense tissue masses with abnormal blood vessel...
1. Following a chemical library screen, the compound 4-hydroxyacetophenone (4-HAP) was found to target mechanical changes in cell shape important...
1. The newly discovered antibacterial compound teixobactin, isolated from the soil bacteria Eleftheria terrae, targeted cell wall synthesis in gram-positive...
1. A polymer scaffold modified with stimulatory molecules promoted the growth and migration of tumor-specific immune T cells in vitro...
1. Nanoparticles loaded with proteasomes, protein complexes that degrade defective proteins, were nontoxic and readily taken up by cells in...
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