Ceritinib shows good activity against tumors with ALK rearrangements
Image: PD 1. There was a 58% response rate to ceritinib among non-small-cell lung cancer (NSCLC) patients. 2. Median progression-free...
SPCG-4 trial: Radical prostatectomy superior to watchful waiting
Image: PD 1. Radical prostatectomy for early, localized prostate cancer led to better overall survival compared to watchful waiting. 2....
First line bevacizumab fails to improve survival newly diagnosed glioblastoma patients [AVAglio trial]
Image: PD 1. Bevacizumab as a first-line agent alongside temozolomide and radiotherapy increased progression-free survival, but did not increase overall...
![Macitentan better than placebo for preventing progression of pulmonary arterial hypertension [SERAPHIN Trial]](https://www.2minutemedicine.com/wp-content/uploads/2013/08/ca68dc0329bef0b42ccae7b6656a0f_gallery-350x250.jpg)
Macitentan better than placebo for preventing progression of pulmonary arterial hypertension [SERAPHIN Trial]
Image: CC 1. Macitentan, a derivative of the endothelin receptor antagonist bosentan, reduced morbidity from pulmonary arterial hypertension compared to...
Phase III trial shows survival benefit for early multiple myeloma
Image: CC/Osaro 1. Treatment with lenalidomide and dexamethasone significantly delayed disease progression in patients with smoldering multiple myeloma who were...
New genetic link in pulmonary arterial hypertension holds therapeutic promise
Image: PD 1. A new link has been found between KCNK3 gene mutations and pulmonary arterial hypertension. 2. The mutations...