Obstetrics

Reports of high-impact obstetrics and gynecology studies by medical professionals

Vaginal Lactoferrin administration decreases oxidative stress in the amniotic fluid of pregnant women

1. Administration of vaginal lactoferrin 4 hours before amniocentesis decreased markers of oxidative stress. Evidence Rating Level: 2 (Good) While reactive oxygen species (ROS) are a...

Clinical exome sequencing of stillbirths provides insight into critical genes for fetal survival

1. In this retrospective case-control series, 8.5% of cases received a probable molecular diagnosis based on clinical exome sequencing 2. Loss-of-function variants in genes with...

Iodine deficiency associated with adverse fetal and gestational outcomes

1. Low iodine intake associated with decreased subfecundity, reduced fetal growth, increased preterm delivery, and increased preeclampsia. Evidence Rating Level: 2 (Good) The thyroid gland is...

Dihydroartemisinin-piperaquine versus sulfadoxine-pyrimethamine on the incidence of malaria in infancy

1. No overall significant difference was found in infant malaria incidence between mothers taking intermittent preventive treatment (IPTp) with sulfadoxine-pyrimethamine versus dihydroartemisinin-piperaquine. 2. Dihydroartemisinin-piperaquine (DP)...

Usage of first-line antidepressant medications in early pregnancy associated with selected birth defects

1. Many first-line agents for depression and anxiety – including specific SSRIs, bupropion, and especially venlafaxine – were associated with an increased risk of...

Further evidence that Zika virus disease associated with brain and eye birth defects

1. The prevalence of brain and eye defects was elevated during the 2015-2016 Zika virus outbreak in Colombia compared to the periods immediately before...

Breastfeeding recommended as primary neonatal analgesic in low resource settings

1. Breastfeeding was recommended as a first-line neonatal analgesic for procedures done in non-tertiary care in Kenya. 2. When breastfeeding is unavailable, expressed breastmilk was...

Lung recruitment improves efficacy of surfactant treatment in extremely preterm neonates

1. The intubation-recruitment-surfactant administration-extubation procedure reduced the need for invasive ventilation in extremely preterm neonates compared to those not receiving lung recruitment. 2. There...

Neonatal outcomes in 29 pregnant women with COVID-19: A retrospective study in Wuhan, China

1. Approximately 41.4% of neonates born to COVID-19-positive women in Wuhan, China presented with radiological findings of pneumonia 2. Limited sample size and comparisons limit...

Perinatal transmission of COVID-19 unlikely to occur with appropriate infection control strategies

1. Among neonates born to SARS-CoV-2-positive mothers in three New York Hospitals, none tested positive, or were symptomatic, for the virus at 24 h...
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