Aflibercept monotherapy equivalent to bevacizumab first for diabetic macular edema
1. In patients with diabetic macular edema, aflibercept monotherapy showed no difference in vision improvement compared to step therapy of...
Ophthalmology
Reports of high-impact ophthalmology studies by medical professionals
Subthreshold micropulse laser is equivalent to standard laser for treating diabetic macular edema
1. In a randomized trial of about 250 patients with mild or moderate center-involving diabetic macula edema (DME), subthreshold micropulse...
Daily disposable contact lenses may lower risk for Acanthamoeba keratitis
1. In a small case-control study, patients using reusable contact lenses had a 4.14 times higher risk of Acanthamoeba keratitis...
Shorter time to surgical repair of macula-off retinal detachment may improve final visual acuity
1. In a meta-analysis reflecting about 2,000 subjects, patients with macula-off rhegmatogenous retinal detachments (RRDs) who underwent surgical repair within...
Patterns of anti-VEGF treatment for retinopathy of prematurity vary by country
1. In a large, international cohort of infants with retinopathy of prematurity (ROP) treated with intravitreal anti-VEGF injections, the rate...
Risk of post-vitrectomy endophthalmitis may have increased during the COVID-19 pandemic
1. In a retrospective study of about 30,000 patients, the incidence of post-vitrectomy endophthalmitis increased significantly from 0.11% to 0.21%...
Heavy smoking is associated with visual field loss in glaucoma
1. In a cohort of about 500 eyes with primary open-angle glaucoma (POAG), higher smoking intensity in pack-years was significantly...
No therapies for computer vision syndrome with high certainty evidence in meta-analysis
1. A systematic review and meta-analysis of 45 randomized controlled trials on the treatment of computer vision syndrome (CVS) found...
Monthly brolucizumab is noninferior to aflibercept in treating recalcitrant wet age-related macular degeneration
1. In a phase 3a randomized trial comparing intravitreal brolucizumab to aflibercept for refractory neovascular age-related macular degeneration (nAMD), there...
Serum lipid levels are positively associated with intraocular pressure
1. In a cohort of 100,000 patients, increased levels of total cholesterol, high-density lipoprotein (HDL) cholesterol, and low-density lipoprotein (LDL)...
