• About
  • Masthead
  • License Content
  • Advertise
  • Submit Press Release
  • RSS/Email List
  • Write for us
  • Contact us
2 Minute Medicine
No Result
View All Result

No products in the cart.

SUBSCRIBE
  • Specialties
    • Cardiology
    • Chronic Disease
    • Dermatology
    • Emergency
    • Endocrinology
    • Gastroenterology
    • Imaging and Intervention
    • Infectious Disease
    • Nephrology
    • Neurology
    • Obstetrics
    • Oncology
    • Ophthalmology
    • Pediatrics
    • Preclinical
    • Psychiatry
    • Public Health
    • Pulmonology
    • Rheumatology
    • Surgery
  • Wellness
  • Classics™
    • 2MM+ Online Access
    • Paperback and Ebook
  • Rewinds
  • Visual
  • Partners
    • License Content
    • Submit Press Release
    • Advertise with Us
  • AccountLog-in/out
    • Subscribe
    • Sign-in
    • My account
2 Minute Medicine
  • Specialties
    • Cardiology
    • Chronic Disease
    • Dermatology
    • Emergency
    • Endocrinology
    • Gastroenterology
    • Imaging and Intervention
    • Infectious Disease
    • Nephrology
    • Neurology
    • Obstetrics
    • Oncology
    • Ophthalmology
    • Pediatrics
    • Preclinical
    • Psychiatry
    • Public Health
    • Pulmonology
    • Rheumatology
    • Surgery
  • Wellness
  • Classics™
    • 2MM+ Online Access
    • Paperback and Ebook
  • Rewinds
  • Visual
  • Partners
    • License Content
    • Submit Press Release
    • Advertise with Us
  • AccountLog-in/out
    • Subscribe
    • Sign-in
    • My account
SUBSCRIBE
2 Minute Medicine
Subscribe
Home All Specialties Obstetrics

In utero opiate exposure associated with failed car seat tolerance

byPuja UmaretiyaandLeah Carr, MD
June 15, 2015
in Obstetrics, Pediatrics
Reading Time: 2 mins read
0
Share on FacebookShare on Twitter

1. This retrospective cohort of 220 full-term, low birth weight infants had a car seat tolerance screening failure incidence of 4.8%. Maternal opiate use was associated with car seat tolerance screen failure.

2. Gender, race, delivery mode, single vs. multiple gestation, birth weight, birth gestational age, Apgar score, and positive pressure ventilation use or respiratory support were not associated with car seat tolerance screening failure.

Evidence Rating Level: 2 (Good)

Study Rundown: Car seat tolerance screening (CSTS) for an observation period of 90 to 120 minutes or the duration of the car ride home is recommended for all preterm infants (less than 37 weeks gestational age). However, CSTS practices for low birth weight (LBW, < 2.5 kg) infants varies among institution. This retrospective study sought to identify factors associated with CSTS failure in low birth weight infants. There was an overall CSTS failure rate of 4.8% over the 4-year study period. Maternal urine toxicology screen positive for opiates was associated with an increased incidence of failed car seat tolerance. Otherwise, birth factors including gender, race, delivery mode, singleton vs. multiple gestation, maternal anesthesia, maternal morphine, birth weight, birth gestational age, Apgar score, positive pressure ventilation use, or respiratory support were not associated with CSTS failure. This study was limited by retrospective design and a conservative saturation failure of < 88% that is not universal among hospitals. However, this study identifies that LBW infants exposed to in utero opiates may have a higher risk of CSTS failure and physicians may seek to selectively screen this population.

Click to read the study, published today in Pediatrics

 

Relevant Reading: Relationship of maternal substance abuse to subsequent sudden infant death syndrome in offspring

RELATED REPORTS

Noninvasive ventilation with neurally adjusted ventilatory assist (NIV-NAVA) outperforms nasal continuous positive airway pressure (NCPAP) post-extubation in preterm infants

Antenatal corticosteroids may affect neurodevelopment differently based on gestational age

Rapid genotyping for variant associated with aminoglycoside-induced ototoxicity is feasible in acute neonatal setting

 

In-Depth [retrospective cohort]: A total of 220 full-term (gestational age > 37 weeks) LBW infants participated in the study over a 4-year study period. CSTS involved a period of observation reater than or equal to 90 minutes or estimated duration of travel time home, whichever is longer. Failure was defined as apnea, absence of respirations of > 20 seconds, bradycardia (heart rate < 80 beats per minute) and oxygen desaturation to <88%. Of the 187 infants with complete data, 49% were male, 86.4% were black and 8.5% were white, and 66.3% were born via vaginal delivery. Overall incidence of car seat tolerance screen failure was 4.8% in this cohort. Among the 9 infants who failed the screen, 2 (22.2%) had mothers with positive urine opiate screen, compared to 10 (5.6%) infants who passed the car seat tolerance screen (p = 0.0473). No other factors were associated with car seat tolerance screen failure.

Image: PD

©2015 2 Minute Medicine, Inc. All rights reserved. No works may be reproduced without expressed written consent from 2 Minute Medicine, Inc. Inquire about licensing here. No article should be construed as medical advice and is not intended as such by the authors or by 2 Minute Medicine, Inc.

Tags: car seat trialintrauterine drug exposureneonatology
Previous Post

Exclusive breastfeeding linked to decrease in dental malocclusions

Next Post

2 Minute Medicine Rewind June 8 – June 14, 2015

RelatedReports

No decrease in infant mortality with maternal micronutrient supplementation in Bangladesh
Pediatrics

Noninvasive ventilation with neurally adjusted ventilatory assist (NIV-NAVA) outperforms nasal continuous positive airway pressure (NCPAP) post-extubation in preterm infants

May 6, 2022
Abusive head trauma results in fewer productive life-years
Chronic Disease

Antenatal corticosteroids may affect neurodevelopment differently based on gestational age

April 28, 2022
Oophorectomy associated with reduced cancer risk and all-cause mortality for BRCA1/2 patients
Genetics

Rapid genotyping for variant associated with aminoglycoside-induced ototoxicity is feasible in acute neonatal setting

April 6, 2022
Abusive head trauma results in fewer productive life-years
Chronic Disease

Very low birth weight associated with brain volume differences in adulthood

March 23, 2022
Next Post
Stroke expansion following intra-arterial therapy may explain worse outcomes

2 Minute Medicine Rewind June 8 – June 14, 2015

Arterial recanalization may not indicate reperfusion in ischemic stroke

Unclear if medical therapy management improves health outcomes

Insufficient evidence for treatments of myalgic encephalomyelitis/chronic fatigue syndrome

License Our Award-Winning Physician-Written Medical News and Visual Abstracts

2 Minute Medicine is the leading authoritative medical news licensing service, and the only with reports written by practicing doctors.

LICENSE CONTENT

Get 2MM+ Premium Access

No ads & unlimited access to all current reports, over 9000 searchable archived reports, visual abstracts, Weekly Rewinds, and the online edition of The Classics Series™ textbook.

Subscription Options
2 Minute Medicine

2 Minute Medicine® is an award winning, physician-run, expert medical media company. Our content is curated, written and edited by practicing health professionals who have clinical and scientific expertise in their field of reporting. Our editorial management team is comprised of highly-trained MD physicians. Join numerous brands, companies, and hospitals who trust our licensed content.

Recent Reports

  • Wellness Check: Mental Health
  • #VisualAbstract: Addition of elotuzumab to lenalidomide and dexamethasone did not significantly improve survival outcomes in newly diagnosed, transplant-ineligible multiple myeloma
  • #VisualAbstract: Pretreatment with radiotherapy and two cycles of concurrent cisplatin may reduce toxicity in locally advanced nasopharyngeal carcinoma
License Content
Terms of Use | Disclaimer
Cookie Policy
Privacy Statement (EU)
Disclaimer

© 2021 2 Minute Medicine, Inc. - Physician-written medical news.

  • Specialties
    • Cardiology
    • Chronic Disease
    • Dermatology
    • Emergency
    • Endocrinology
    • Gastroenterology
    • Imaging and Intervention
    • Infectious Disease
    • Nephrology
    • Neurology
    • Obstetrics
    • Oncology
    • Ophthalmology
    • Pediatrics
    • Preclinical
    • Psychiatry
    • Public Health
    • Pulmonology
    • Rheumatology
    • Surgery
  • Wellness
  • Classics™
    • 2MM+ Online Access
    • Paperback and Ebook
  • Rewinds
  • Visual
  • Partners
    • License Content
    • Submit Press Release
    • Advertise with Us
  • Account
    • Subscribe
    • Sign-in
    • My account

© 2021 2 Minute Medicine, Inc. - Physician-written medical news.