Tag: neonatology

1. Apgar scores at five and ten minutes after birth provided prognostic information for preterm infants regarding neonatal survival. 2. Lower Apgar scores for older gestational age infants were associated with increased neonatal death compared to younger gestational age infants with similar scores. Evidence Rating Level: 2 (Good) Study Rundown: Preterm birth...

1. In a retrospective cohort study of almost 50 000 very low birth weight infants (VLBW), overall survival without major morbidity increased significantly between 2008 and 2017. 2. The largest improvements in major morbidity rates were seen for nosocomial infection (NI) and necrotizing enterocolitis (NEC), while the rates of bronchopulmonary...

1. The American Academy of Pediatrics (AAP) recommends that newborns born to mothers affected by or being tested for COVID-19 be temporarily separated from their mothers. It is also recommended that these infants be separated from newborns born to unaffected mothers in order to reduce risk of transmission. 2. The...

1. A multicenter randomized control trial concluded that n-3 polyunsaturated fatty acid supplementation in pregnancy did not change the risk of preterm delivery or the risk of post-term induction or cesarean section. 2. The safety profile of n-3 polyunsaturated fatty acid supplementation in pregnancy was similar to control. Evidence Rating Level:...

1. A multicenter randomized control trial concluded that n-3 polyunsaturated fatty acid supplementation in pregnancy did not change the risk of preterm delivery or the risk of post-term induction or cesarean section. 2. The safety profile of n-3 polyunsaturated fatty acid supplementation in pregnancy was similar to control. Evidence Rating...

1. Extremely preterm infants born in non-tertiary hospitals in England had an increased risk of death, and transfer in the first 48 hours postnatally was associated with increased risk of severe brain injury relative to infants born in tertiary neonatal care. Evidence Rating Level: 2 (Good) Extremely preterm infants born at...

1. Across the state of California, there was greater than 100-fold variability in the number of infants treated with antibiotics per proven bloodstream infection, ranging from 7.3 to 781 infants treated. 2. The number of infants exposed to antibiotics correlated strongly with the number of live births admitted to the...

1. Preterm infants given prophylactic platelet transfusions at thresholds below 50,000 platelets per cubic millimeter had higher risks of death or major bleeding after 28 days as compared to neonates given transfusions at thresholds below 25,000 per cubic millimeter. 2. There was no significant difference in other serious adverse events...

Little is known about the survival and neurodevelopmental outcomes of extremely preterm infants with low birth weight. More data is needed to facilitate decisions regarding the initiation of treatment and resuscitation in this population. In this retrospective cohort study, 205 infants born between 22 and 26 weeks gestational age...

1. For preterm infants with echocardiographically-confirmed patent ductus arteriosus (PDA) within the first 14 days of life, there was no significant difference in the timing of PDA closure between infants who received liberal versus restrictive platelet transfusions. 2. Infants in the liberal transfusion group had significantly higher rates of intraventricular...