• About
  • Masthead
  • License Content
  • Advertise
  • Submit Press Release
  • RSS/Email List
  • 2MM Podcast
  • Write for us
  • Contact Us
2 Minute Medicine
No Result
View All Result

No products in the cart.

SUBSCRIBE
  • Specialties
    • All Specialties, All Recent Reports
    • Cardiology
    • Chronic Disease
    • Dermatology
    • Emergency
    • Endocrinology
    • Gastroenterology
    • Imaging and Intervention
    • Infectious Disease
    • Nephrology
    • Neurology
    • Obstetrics
    • Oncology
    • Ophthalmology
    • Pediatrics
    • Pharma
    • Preclinical
    • Psychiatry
    • Public Health
    • Pulmonology
    • Rheumatology
    • Surgery
  • AI Roundup
  • Pharma
  • The Scan+
  • Classics™+
    • 2MM+ Online Access
    • Paperback and Ebook
  • Rewinds
  • Visual
  • Podcasts
  • Partners
    • License Content
    • Submit Press Release
    • Advertise with Us
  • Account
    • Subscribe
    • Sign-in
    • My account
2 Minute Medicine
  • Specialties
    • All Specialties, All Recent Reports
    • Cardiology
    • Chronic Disease
    • Dermatology
    • Emergency
    • Endocrinology
    • Gastroenterology
    • Imaging and Intervention
    • Infectious Disease
    • Nephrology
    • Neurology
    • Obstetrics
    • Oncology
    • Ophthalmology
    • Pediatrics
    • Pharma
    • Preclinical
    • Psychiatry
    • Public Health
    • Pulmonology
    • Rheumatology
    • Surgery
  • AI Roundup
  • Pharma
  • The Scan+
  • Classics™+
    • 2MM+ Online Access
    • Paperback and Ebook
  • Rewinds
  • Visual
  • Podcasts
  • Partners
    • License Content
    • Submit Press Release
    • Advertise with Us
  • Account
    • Subscribe
    • Sign-in
    • My account
SUBSCRIBE
2 Minute Medicine
Subscribe
Home All Specialties Chronic Disease

Nutritional supplements do not significantly affect cognitive function in the elderly

byPriyanka Vedak
August 26, 2015
in Chronic Disease, Neurology
Reading Time: 2 mins read
0
Share on FacebookShare on Twitter

1. Supplementation with omega-3 fatty acids, lutein or zeaxanthin did not significantly impact the cognitive function of the elderly adults examined in this study over a 5-year period.

2. There was also no significant difference in cognitive function between study participants randomized to receive high-zinc versus low-zinc or between those randomized to beta-carotene versus placebo.

Evidence Rating Level: 1 (Excellent) 

Study Rundown: Prior studies have demonstrated variable results regarding the protective effect of nutritional supplements, including omega-3 fatty acids, lutein, and zeaxanthin on cognitive function. This study evaluated the role of these nutritional supplements on cognitive function by using data from cognitive function tests performed on participants who were enrolled in a separate trial that was examining the role of these supplements in treating age-related macular degeneration and cataracts. This study found that there was no significant effect of supplementation with omega-3 fatty acids, lutein or zeaxanthin on the cognitive function of the elderly adults examined over the 5-year period. There was also no significant difference in cognitive function between study participants randomized to receive high-zinc versus low-zinc or between those randomized to beta-carotene versus placebo.

While this study was strengthened by its randomized controlled design and high supplementation adherence rates, limitations include difficulties with generalizability given that the study design focused on a select population of elderly adults with age-related macular degeneration and cataracts. The 5-year study period may also have been too short to detect effects of nutritional supplementation on cognition. Overall, this study does not support the use of nutritional supplementation to protect against cognitive decline.

Click to read the study, published today in JAMA

RELATED REPORTS

Nivolumab plus ipilimumab improves survival over lenvatinib or sorafenib in liver cancer

Dapagliflozin may improve outcomes in patients with metabolic dysfunction-associated steatohepatitis

Early induction of labour reduces shoulder dystocia rates in large for gestational age fetuses

Click to read the accompanying editorial, published today in JAMA

Relevant Reading: A randomized trial of vitamin E supplementation and cognitive function in women

In-Depth [randomized controlled trial]: This study examined 3073 participants of the AREDS2 trial who consented to cognitive function testing and who were not eliminated by exclusion criteria aimed at eliminating participants with missing data. The mean age of participants was 72.7 years. Cognitive function testing was performed at baseline, 2 years, and 4 years. The difference between the yearly change in the composite cognitive function score of participants was not significantly different for any of the comparisons in this study, which were omega-3 versus placebo (-0.03, 99%CI -0.20 to 0.13, p = 0.63), lutein/zeaxanthin versus placebo (-0.01, 99%CI 0.87 to 1.33, p = 0.80), high-zinc versus low-zinc was (-0.01, 99%CI -0.18 to 0.16, p = 0.89), and beta-carotene versus placebo (-0.11, 99%CI -0.28 to 0.07, p = 0.12).

Image: PD

©2015 2 Minute Medicine, Inc. All rights reserved. No works may be reproduced without expressed written consent from 2 Minute Medicine, Inc. Inquire about licensing here. No article should be construed as medical advice and is not intended as such by the authors or by 2 Minute Medicine, Inc.

Previous Post

Discontinuation of antihypertensives may not improve cognitive function in elderly [DANTE study]

Next Post

Image-guided percutaneous drainage of pericardial effusions is safe and effective

RelatedReports

Prognostic indicators for transarterial chemoembolization in patients with hepatocellular carcinoma with extrahepatic spread identified
AI Roundup

Nivolumab plus ipilimumab improves survival over lenvatinib or sorafenib in liver cancer

June 12, 2025
Intrapartum serum prolactin may predict risk of postpartum diabetes
Chronic Disease

Dapagliflozin may improve outcomes in patients with metabolic dysfunction-associated steatohepatitis

June 11, 2025
Late gestation antidepressant use linked to postpartum hemorrhage
Obstetrics

Early induction of labour reduces shoulder dystocia rates in large for gestational age fetuses

June 11, 2025
Lessons from real-world implementation of lung cancer screening
AI Roundup

Sacituzumab tirumotecan may have a role in the treatment of metastatic non-small cell lung cancer

June 10, 2025
Next Post
Image-guided percutaneous drainage of pericardial effusions is safe and effective

Image-guided percutaneous drainage of pericardial effusions is safe and effective

Uninterrupted warfarin therapy safe for endovascular procedures

Sleep deprivation in attending physicians not linked to adverse outcomes in elective daytime surgical procedures

Vaccines for predicted influenza strains may provide wide protection [PreClinical]

Novel human antibody protects mice from H7N9 flu virus [PreClinical]

2 Minute Medicine® is an award winning, physician-run, expert medical media company. Our content is curated, written and edited by practicing health professionals who have clinical and scientific expertise in their field of reporting. Our editorial management team is comprised of highly-trained MD physicians. Join numerous brands, companies, and hospitals who trust our licensed content.

Recent Reports

  • Nivolumab plus ipilimumab improves survival over lenvatinib or sorafenib in liver cancer
  • Dapagliflozin may improve outcomes in patients with metabolic dysfunction-associated steatohepatitis
  • Early induction of labour reduces shoulder dystocia rates in large for gestational age fetuses
License Content
Terms of Use | Disclaimer
Cookie Policy
Privacy Statement (EU)
Disclaimer

© 2021 2 Minute Medicine, Inc. - Physician-written medical news.

  • Specialties
    • All Specialties, All Recent Reports
    • Cardiology
    • Chronic Disease
    • Dermatology
    • Emergency
    • Endocrinology
    • Gastroenterology
    • Imaging and Intervention
    • Infectious Disease
    • Nephrology
    • Neurology
    • Obstetrics
    • Oncology
    • Ophthalmology
    • Pediatrics
    • Pharma
    • Preclinical
    • Psychiatry
    • Public Health
    • Pulmonology
    • Rheumatology
    • Surgery
  • AI Roundup
  • Pharma
  • The Scan
  • Classics™
    • 2MM+ Online Access
    • Paperback and Ebook
  • Rewinds
  • Visual
  • Podcasts
  • Partners
    • License Content
    • Submit Press Release
    • Advertise with Us
  • Account
    • Subscribe
    • Sign-in
    • My account
No Result
View All Result

© 2021 2 Minute Medicine, Inc. - Physician-written medical news.