• About
  • Masthead
  • License Content
  • Advertise
  • Submit Press Release
  • RSS/Email List
  • 2MM Podcast
  • Write for us
  • Contact Us
2 Minute Medicine
No Result
View All Result

No products in the cart.

SUBSCRIBE
  • Specialties
    • All Specialties, All Recent Reports
    • Cardiology
    • Chronic Disease
    • Dermatology
    • Emergency
    • Endocrinology
    • Gastroenterology
    • Imaging and Intervention
    • Infectious Disease
    • Nephrology
    • Neurology
    • Obstetrics
    • Oncology
    • Ophthalmology
    • Pediatrics
    • Pharma
    • Preclinical
    • Psychiatry
    • Public Health
    • Pulmonology
    • Rheumatology
    • Surgery
  • AI Roundup
  • Pharma
  • The Scan+
  • Classics™+
    • 2MM+ Online Access
    • Paperback and Ebook
  • Rewinds
  • Visual
  • Podcasts
  • Partners
    • License Content
    • Submit Press Release
    • Advertise with Us
  • Account
    • Subscribe
    • Sign-in
    • My account
2 Minute Medicine
  • Specialties
    • All Specialties, All Recent Reports
    • Cardiology
    • Chronic Disease
    • Dermatology
    • Emergency
    • Endocrinology
    • Gastroenterology
    • Imaging and Intervention
    • Infectious Disease
    • Nephrology
    • Neurology
    • Obstetrics
    • Oncology
    • Ophthalmology
    • Pediatrics
    • Pharma
    • Preclinical
    • Psychiatry
    • Public Health
    • Pulmonology
    • Rheumatology
    • Surgery
  • AI Roundup
  • Pharma
  • The Scan+
  • Classics™+
    • 2MM+ Online Access
    • Paperback and Ebook
  • Rewinds
  • Visual
  • Podcasts
  • Partners
    • License Content
    • Submit Press Release
    • Advertise with Us
  • Account
    • Subscribe
    • Sign-in
    • My account
SUBSCRIBE
2 Minute Medicine
Subscribe
Home All Specialties Cardiology

Survivorship trends for children and young adults with congenital heart disease

byJames EnglandandAnees Daud
December 21, 2016
in Cardiology, Pediatrics, Surgery
Reading Time: 2 mins read
0
Share on FacebookShare on Twitter

1. Based on a Swedish registry, survivorship for children and young adults with congenital heart disease (CHD) improved for children since 1970, with the largest improvements occurring in the cohort born between 1990 to 1993.

2. Despite improvement in outcomes, mortality amongst those with congenital heart disease remains significantly higher compared with the general population.

Evidence Rating Level: 2 (Good)

Study Rundown: Improvements in surgical techniques, and neonatal and perioperative care have led to substantial improvements in short term survival for children born with congenital heart disease (CHD). This prospective study using the nationwide registry for CHD in Sweden sought to describe trends in mortality for children with CHD over time and compared to matched controls from the general population.

There were 21 982 patients with CHD born between 1970 and 1993 in Sweden that were identified in the registry. Mortality for the CHD group was higher compared to the general population matched-control group, with both higher- and lower-risk congenital anomaly groups experiencing increased mortality. Mortality was highest for children aged 4-years and under. Through the different time periods, mortality for younger age groups decreased for children born in the 1990s compared to 1970s. Young adults (>18 years) demonstrated no improvement in survivorship through the different time periods. The strengths of the study included the design (large, population-wide study) and the long-term follow-up. A major limitation of the study was the reliance on diagnostic codes and databases to identify patients, which may be incomplete, especially for the older outpatient registries.

Click to read the study, published today in JAMA Internal Medicine

RELATED REPORTS

Screening model examines neonatal detection of congenital heart defects

No link between antidepressant use in pregnancy and fetal cardiac abnormalities

Pulse oximetry screening improved detection of congenital heart disease in China

Relevant Reading: Survival Prospects and Circumstances of Death in Contemporary Adult Congenital Heart Disease Patients Under Follow-Up at a Large Tertiary Centre

In-Depth [case-control study]: This study used data from the Swedish National Patient Registry and the National Hospital Outpatient Register to enroll people born between 1970 and 1993 who had a diagnosis of CHD as identified by diagnostic codes in discharges summaries, operative reports, or other records. Each CHD patient was matched by birth year, sex, and county to 9-10 control individuals without a diagnosis of CHD. CHD was categorized by hierarchy into 5 groups based on underlying anatomic pathology.

For individuals with CHD, mortality was higher compared to controls (HR 16.51, 95%CI 15.29-17.83; p < 0.001). In the youngest age group (≤4 years), HR for mortality decreased from 1970-1979 to 1990-1993 (HR 225.84, 95%CI 136.84-372.70; to 33.47, 95%CI 22.54-49.70). For young adults, the hazard ratios for mortality did not significantly decrease over time: 1970 to 1979 HR 7.79 (95%CI 6.72-8.96),1980-1989 HR4.91 (95%CI 3.99-6.02), and 1990-1993 HR 4.26 (95%CI 2.29-7.94).

Image: PD

©2016 2 Minute Medicine, Inc. All rights reserved. No works may be reproduced without expressed written consent from 2 Minute Medicine, Inc. Inquire about licensing here. No article should be construed as medical advice and is not intended as such by the authors or by 2 Minute Medicine, Inc.

Tags: congenital heart defects
Previous Post

No association found between length of storage for transfused red blood cells and patient mortality

Next Post

Dry cord care non-inferior to antiseptic care

RelatedReports

Noninvasive ventilation strategies examined in NICU infants
Cardiology

Screening model examines neonatal detection of congenital heart defects

May 11, 2015
Mediterranean diet linked to reduced diabetes risk in high risk cardiovascular patients
Obstetrics

No link between antidepressant use in pregnancy and fetal cardiac abnormalities

June 19, 2014
Mediterranean diet linked to reduced diabetes risk in high risk cardiovascular patients
Cardiology

Pulse oximetry screening improved detection of congenital heart disease in China

April 25, 2014
Mediterranean diet linked to reduced diabetes risk in high risk cardiovascular patients
Cardiology

First trimester biomarkers screen for congenital heart defects

April 9, 2014
Next Post
California’s cystic fibrosis newborn screening model is highly effective

Dry cord care non-inferior to antiseptic care

Parents with poor sleep quality report sleep problems in kids

Shorter courses of antibiotics for otitis media less effective in children

Corticosteroids improve outcomes in treatment of community-acquired pneumonia

Induced hypothermia not associated with improved outcomes for status epilepticus: The HYBERNATUS study

2 Minute Medicine® is an award winning, physician-run, expert medical media company. Our content is curated, written and edited by practicing health professionals who have clinical and scientific expertise in their field of reporting. Our editorial management team is comprised of highly-trained MD physicians. Join numerous brands, companies, and hospitals who trust our licensed content.

Recent Reports

  • Time-restricted eating does not confer changes in sleep, mood, or quality of life
  • Commonly cited medication triggers may not increase risk of microscopic colitis among older adults
  • Ablation may reduce stroke risk, death, heart failure hospitalization in patients with atrial fibrillation
License Content
Terms of Use | Disclaimer
Cookie Policy
Privacy Statement (EU)
Disclaimer

© 2021 2 Minute Medicine, Inc. - Physician-written medical news.

  • Specialties
    • All Specialties, All Recent Reports
    • Cardiology
    • Chronic Disease
    • Dermatology
    • Emergency
    • Endocrinology
    • Gastroenterology
    • Imaging and Intervention
    • Infectious Disease
    • Nephrology
    • Neurology
    • Obstetrics
    • Oncology
    • Ophthalmology
    • Pediatrics
    • Pharma
    • Preclinical
    • Psychiatry
    • Public Health
    • Pulmonology
    • Rheumatology
    • Surgery
  • AI Roundup
  • Pharma
  • The Scan
  • Classics™
    • 2MM+ Online Access
    • Paperback and Ebook
  • Rewinds
  • Visual
  • Podcasts
  • Partners
    • License Content
    • Submit Press Release
    • Advertise with Us
  • Account
    • Subscribe
    • Sign-in
    • My account
No Result
View All Result

© 2021 2 Minute Medicine, Inc. - Physician-written medical news.