Tag: antidepressants

1. Many first-line agents for depression and anxiety – including specific SSRIs, bupropion, and especially venlafaxine – were associated with an increased risk of birth defects if used during early pregnancy. Evidence Level Rating: 2 (Good) The management of depression and anxiety during pregnancy is challenging, especially considering that they affect...
Robotic Approach to Paraesophageal Hernia Repair Results in Low Long-Term Recurrence Rate and Beneficial Patient-Centered Outcomes 1. The use of robotic techniques to repair paraesophageal hernias resulted in low rates of recurrence and had positive patient outcomes at five years. Evidence Rating Level: 3 (Average) Since the advent of laparoscopic surgery in...
1. Parents of children newly diagnosed with cancer had significantly increased risk for a first prescription of antidepressants, anxiolytics, and hypnotics in the initial year following diagnosis. 2. There was no difference in risk for first prescription of psychotropic medication depending on cancer type. The greatest increase in risk was...
1. Neonatal intensive care unit (NICU) admittance was higher among infants born to women receiving selective serotonin reuptake inhibitors (SSRIs) during pregnancy compared to nonexposed infants. 2. Maternal SSRI use during late pregnancy was associated with an increase in infant respiratory and CNS-related disorders, hypoglycemia, and feeding difficulties compared to...
1. Antidepressant use during a given menstrual cycle was associated with decreased fecundability during that cycle. 2. History of anxiety or depression was not independently associated with decreased fertility. Evidence Rating Level: 2 (Good) Study Rundown: Antidepressants are one of the most frequently prescribed classes of drugs in the United States. Overall,...
1. In a retrospective cohort study of over 21 000 patients with depression, antidepressant use was significantly associated with an increased incidence of manic episode/bipolar disorder. 2. The strongest association was found in those patients who had previously taken selective serotonin reuptake inhibitors (SSRIs) or venlafaxine. Evidence Rating Level: 3 (Average) Study...