1. Patients with heart failure may experience a nearly two-fold increase in mortality risk during the next year after an outpatient intensification of diuretic therapy.
Evidence Rating Level: 2 (Good)
Hospitalizations are associated with increased mortality risk after discharge in patients with decompensated heart failure, with intensifying diuretic therapy being one...
1. Use of medications to inhibit the renin-angiotensin system (RAS) following transcatheter aortic valve replacement (TAVR) for severe aortic stenosis linked with reduced cardiac mortality at 3 years.
2. RAS inhibition was also demonstrated to have a greater reduction in ventricular volume and septal hypertrophy on follow-up echocardiogram.
Evidence Rating Level:...
1. Irbesartan was associated with a significantly lower risk of doubling of serum creatinine concentration, developing end-stage renal disease, or death from all causes.
2. Serum creatinine concentration increased at a slower rate in patients receiving irbesartan compared to amlodipine and placebo groups.
Original Date of Publication: September 20, 2001