Tag: coronary artery disease (CAD)

1. Patients with severely reduced left ventricular ejection fraction with left main, left anterior descending, or multivessel disease who underwent percutaneous coronary intervention demonstrated higher rates of mortality and major adverse cardiovascular events compared to those who underwent coronary artery bypass grafting. Evidence Rating Level: 2 (Good) There is insufficient evidence in...
1. Total arterial vascularization (TAR) resulted in reduced likelihood of myocardial infarction, major cardio- and cerebrovascular events, and death compared to non-TAR in those requiring coronary artery bypass grafting. Evidence Rating Level: 2 (Good) Given the discussion surrounding multivessel coronary artery disease and the ideal conduits for coronary artery bypass grafting (CABG),...
With the large and growing population of cancer survivors over the last several decades, there exists significant concern that these patients may be at an increased risk of cardiovascular disease. However, few studies have examined risks of multiple specific outcomes of cardiovascular disease in survivors of a wide range...
The current standard therapy following percutaneous coronary intervention (PCI) with drug-eluting stents (DES) is dual antiplatelet therapy (DAPT) with aspirin plus a P2Y12 inhibitor, followed by aspirin (ASA) monotherapy. P2Y12 inhibitor monotherapy has recently been suggested as an alternative to DAPT, with studies showing reduced risk of subsequent ischemic...
Computed tomography angiography (CTA) is being increasingly used in evaluating patients with suspected coronary artery disease (CAD) and possible angina. It is currently unclear, however, which patient subgroups in which CTA demonstrates the highest diagnostic clinical performance. In this meta-analysis, individual patient data (n=5332) from 64 prospective diagnostic accuracy...
Suicide in older adults living in or transitioning to residential long-term care, 2003 to 2015 It is estimated that by the year 2050, 1 in 5 individuals will be 65 years or older. In addition to the growing number of seniors in North America, the rate of suicide has also...
The consumption of ultra-processed food has increased substantially over the last several decades. These foods often have higher proportions of total and saturated fat, added sugar, energy density and salt, and lower proportions of fiber and vitamin density. Limited cross-sectional data has suggested associations with obesity, metabolic syndrome, functional...
Rivaroxaban is a selective direct factor Xa inhibitor that has been associated with improved outcomes in stable patients with chronic atherosclerotic cardiovascular disease and acute coronary syndrome. Nevertheless, its role in the treatment of patients with coronary artery disease (CAD) in addition to heart failure remains unclear. In the...
Association Between Longitudinal Plasma Neurofilament Light and Neurodegeneration in Patients With Alzheimer Disease Alzheimer disease (AD) is characterized by the accumulation of amyloid b (Ab) and tau aggregates in the brain. The progression of AD can be monitored through imaging techniques or through the use of cerebrospinal fluid (CSF) biomarkers....
1. Revascularization with percutaneous coronary intervention (PCI) of unprotected left main (ULM) artery remains an infrequently performed procedure in the United States. 2. The patients undergoing PCI for ULM disease are older, with greater comorbidities, and more adverse outcomes than the clinical trial populations. Evidence Rating Level: 3 (Average)        Study Rundown: Left main...