Tag: Cyclosporine

1. Seven years after transplantation, patient and kidney graft survival and function were significantly higher with belatacept than cyclosporine based immunosuppressants. 2. The cumulative frequencies of serious adverse events were similar across both belatacept and cyclosporine groups. Evidence Rating Level: 1 (Excellent) Study Rundown: Renal transplant immunosuppressive therapies usually include calcineurin-inhibitors, like...
1. Conversion at 4.5 months following kidney transplant from cyclosporine (a calcineurin inhibitor) to everolimus (a mTOR pathway inhibitor) maintains improved renal function at 5-year follow-up 2. Although post-conversion everolimus therapy was associated with an increased the rate of acute rejection, it was reversible and did not affect long term...