Tag: dermatology

1. 91% of patients receiving bimekizumab 320 mg every 4 weeks achieved ≥ 90% improvement from baseline in the Psoriasis Area Severity Index (PASI90) compared to 1% receiving placebo. 2. After achieving PASI90 at week 16, bimekizumab response was maintained through week 56 in both dosing schedules (every 4 weeks...
1. Pregnant women using biologic treatments for psoriasis, both before and during pregnancy, were found to have similar pregnancy outcomes as the general American population. Evidence Rating Level: 2 (Good) Psoriasis is a chronic inflammatory skin disease affecting 7 million adults in the United States. It has been hypothesized that the...
Total knee replacement after high tibial osteotomy: time-to-event analysis and predictors 1. 5 and 10 years after undergoing a high tibial osteotomy procedure, 95% and 79% of knee osteoarthritis patients respectively did not require a total knee replacement. 2. Preoperative factors associated with an increased rate of conversion to total knee...
1. Among a large cohort of Danish adults, the use of potent or very potent topical corticosteroids was found to be associated with an increased risk of osteoporosis and major osteoporotic fracture. Evidence Level Rating: 2 (Good) It is well established that in their systemic and inhaled forms, corticosteroids have a...
1. Among patients with cutaneous melanoma, ultrasound evaluation identified in half of patients in-transit metastases that were otherwise not apparent during clinical examination and changed the course of management for a third of patients. Evidence Leve Rating: 3 (Average) In-transit metastases (ITMs), or lesions that develop in lymphatics between the primary...
1. Among patients admitted to the hospital for a provisional diagnosis of cellulitis, early dermatologic consultation was associated with improved recognition of pseudo-cellulitis, decreased antibiotic use, and earlier discharge. 2. For patients in whom pseudo-cellulitis was recognized, antibiotics and in-patient management were less common, while topical steroids and conservative measures...