Tag: Diabetic Nephropathy

1. Serum urate reduction with allopurinol was not shown to clinically benefit kidney function among patients with type 1 diabetes and early-to-moderate diabetic kidney disease. 2. Serum creatinine did not improve following serum urate reduction with allopurinol. Evidence Rating Level: 1 (Excellent) Study Rundown: The lifetime risk of diabetic kidney disease among...
1. In adolescents with type 1 diabetes mellitus, the albumin-to-creatinine ratio was not significantly changed by angiotensin-converting-enzyme (ACE) inhibitors alone, statins alone, or the two in combination compared to placebo. 2. In this population, ACE-inhibitors and statins did not demonstrate a significant benefit on other markers of diabetic vascular complications...
Originally published by Harvard Health. What Is It? Diabetic nephropathy is kidney disease that is a complication of diabetes. It can occur in people with type 2 diabetes, the diabetes type that is most common and is caused by resistance to insulin, or in people with type 1 diabetes, the type...
In this section, we highlight the key high-impact studies, updates, and analyses published in medicine during the past week. Urinary Sodium and Potassium Excretion, Mortality, and Cardiovascular Events Decreased sodium intake is associated with a modest decrease in blood pressure, but it is unclear whether this translates to a decrease in...
Classics Series, Landmark Trials in Medicine
Image: PD 1. In patients with type II diabetes and nephropathy, losartan at a dose of 50-100 mg daily significantly reduced the risk of developing end-stage renal disease compared to placebo. 2. While losartan also significantly reduced the degree of proteinuria in these patients, it did not significantly reduce mortality when...
Image: PD In this section, we will highlight the key high-impact studies, updates, and analyses published in medicine during the past week. Combined Angiotensin Inhibition for the Treatment of Diabetic Nephropathy Diabetic nephropathy is a leading cause of end-stage renal disease (ESRD).  Angiotensin-converting-enzyme (ACE) inhibitors and angiotensin II-receptor blockers (ARBs) are commonly...