Tag: ebola

1. This modeling study showed that if malaria care were to have ceased as a result of the Ebola epidemic, an estimated 3.5 million additional untreated cases of malaria would have occurred in Guinea, Liberia, and Sierra Leone, leading to 10,900 malaria-attributable deaths. 2. If health systems in Guinea, Sierra...
In this section, we highlight the key high-impact studies, updates, and analyses published in medicine during the past week. Age of Transfused Blood in Critically Ill Adults Whether the administration of fresh red blood cells instead of red blood cells that have been stored for a period of time improves outcomes...
In this section, we highlight the key high-impact studies, updates, and analyses published in medicine during the past week. Cell-free DNA Analysis for Noninvasive Examination of Trisomy Cell-free DNA (cfDNA) is obtained from maternal blood samples and has been reported to have a high sensitivity for trisomy 21 and a low...
1. A randomized, double-blind, placebo-controlled phase 1 trial testing a new Ebola virus vaccine specific to the 2014 Zaire Guinea strain was determined to be safe, with mild pain at the injection site being the most common adverse reaction and no serious adverse events reported in 28 days of...
1. In this report of a 44-year-old male exposed to Ebola virus through a needle stick in Sierra Leone, vaccination with an experimental vaccine (VZVDG-ZEBOV) was effective in preventing Ebola virus infection. 2. Laboratory analysis indicated an innate and adaptive immune response after administration of the VZVDG-ZEBOV vaccine. Evidence Rating Level:...
In this section, we highlight the key high-impact studies, updates, and analyses published in medicine during the past week. Improved Overall Survival in Melanoma with Combined Dabrafenib and Trametinib BRAF inhibitors have shown efficacy in the treatment of patients with previously untreated metastatic melanoma with BRAF V600E and V600K mutations. This...
1. The Ebola and Marburg vaccines were shown to be safe and well tolerated when given as part of a series of three injections both as separate and combined vaccinations, with no serious adverse events reported. 2. The Ebola and Marburg vaccines generated virus antigen-specific humoral and cellular immune...
In this section, we highlight the key high-impact studies, updates, and analyses published in medicine during the past week. Association of Sickle Cell Trait With Chronic Kidney Disease and Albuminuria in African Americans Sickle cell trait (SCT), inheritance of a single copy of the sickle hemoglobin mutation, affects 1 in 12...
In this section, we highlight the key high-impact studies, updates, and analyses published in medicine during the past week. Clinical Illness and Outcomes in Patients with Ebola in Sierra Leone With more than 10,100 reported cases, the current Ebola virus disease (EVD) outbreak is the largest and most widespread outbreak in...
In this section, we highlight the key high-impact studies, updates, and analyses published in medicine during the past week. Ebola Virus Disease in West Africa — The First 9 Months of the Epidemic and Forward Projections The current Ebola virus disease (EVD) epidemic in west Africa, first beginning in December 2013,...