Tag: efavirenz

1. Dolutegravir-based antiretroviral therapy regimens effectively suppressed maternal viral load during pregnancy, supporting their use to prevent vertical transmission. 2. Dolutegravir, emtricitabine, and tenofovir alafenamide fumarate carried relatively low risk of adverse fetal outcomes. Evidence Rating Level: 1 (Excellent) Study Rundown: Initiation of antiretroviral therapy (ART) for pregnant women infected with HIV-1...
1. For previously untreated HIV-1 patients in Cameroon, treatment with dolutegravir was noninferior to low dose efavirenz at lowering viral load over a period of 48 weeks. 2. Weight gain occurred in both groups but was more evident in the dolutegravir treated patients. Evidence Rating Level: 1 (Excellent)   Study Rundown: For...
1. Treatment with efavirenz in HIV patients was associated with an increased risk of suicidality.  Evidence Rating Level: 2 (Good)                 Study Rundown: Efavirenz is a common non-nucleoside reverse transcriptase inhibitor (NNRT-I) used in the treatment of human immunodeficiency virus (HIV).  The drug has been...