Apixaban (eliquis) outperforms Rivaroxaban (xarelto) in venous thromboembolism bleeding risk
1. In the randomized COBRRA trial, apixaban was associated with substantially less clinically relevant bleeding than rivaroxaban in patients with ...
Tag: hematology
![2 Minute Medicine: Pharma Roundup: Price Hikes, Breakthrough Approvals, Legal Showdowns, Biotech Expansion, and Europe’s Pricing Debate [May 12nd, 2025]](https://www.2minutemedicine.com/wp-content/uploads/2025/05/ChatGPT-Image-May-12-2025-at-10_22_23-AM-350x250.png)
2 Minute Medicine: Pharma Roundup – Pfizer’s Talzenna delays prostate cancer progression, apixaban lowers VTE bleeding risk, Lilly’s retatrutide hits Phase III metabolic targets, and FDA warns Novo Nordisk over safety reporting violations [March 2026]
Pfizer’s Talzenna combo significantly delays progression in frontline prostate cancer Topline results from the Phase 3 TALAPRO-3 study indicate that ...
FDA grants priority review for iberdomide-based myeloma regimen
1. The FDA has granted priority review for iberdomide, a first-in-class oral CELMoD designed to degrade transcription factors more effectively ...
Effect of high elevation on deep vein thrombosis: a multicenter cohort study
1. Injuries suffered at high elevations are associated with a significantly higher odds of developing deep vein thrombosis (DVT) compared ...
2 Minute Medicine Rewind
Ultrasound-Guided Regional Anesthesia by Emergency Physicians for Hip Fractures and Delirium 1. An intervention to increase point-of-care ultrasound-guided regional anesthesia ...
Pre-maintenance positron emission tomography/computed tomography and bone marrow multiparameter flow cytometry are important for prognostication in multiple myeloma treated with daratumumab
1. Pre-maintenance positron emission tomography (PET)/computed tomography (CT) and bone marrow multiparameter flow cytometry (BM MFC) are associated with better ...
2 Minute Medicine: Pharma Roundup- Obesity RNA deal, at-home Alzheimer’s dosing, oncology royalty financing, and first Bruton’s Tyrosine Kinase Inhibitor for Immune Thrombocytopenia [September 3, 2025]
Novo’s srRNA push expands cardiometabolic pipeline On August 28, Novo Nordisk announced a collaboration with Replicate Bioscience to pursue self ...
Neutrophil-to-lymphocyte ratio may be a useful marker of mortality in septic patients with liver cirrhosis
1. In septic patients with liver cirrhosis, the neutrophil-to-lymphocyte (NLR) ratio was positively correlated with all-cause mortality. Evidence Rating Level: ...
Mitapivat improves clinical outcomes in patients with non-transfusion dependent thalassemia
1. Hemoglobin response was significantly greater in the treatment group compared to placebo. 2. Majority of adverse events were mild ...
Red cell distribution width to albumin ratio may be a useful prognostic marker in the critical care setting
1. Higher red cell distribution width to albumin ratio (RAR) values were associated nonlinearly with a higher mortality risk. 2. ...
