Ruxolitinib results in improved repigmentation as compared to vehicle-control in nonsegmental vitiligo
1. In comparison to vehicle-control, a greater proportion of patients using ruxolitinib achieved a reduction in facial Vitiligo Area Scoring ...
Tag: immunology
ACKR1 variant increases risk of azathioprine-related hematopoietic toxicity
1. Patients with the ACKR1 variant (CC genotype) had an elevated risk of azathioprine discontinuation attributed to hematopoietic toxicity. 2. ...
Intravenous vitamin C increases mortality and organ dysfunction in sepsis patients
1. In patients with sepsis receiving a vasopressor in the intensive care unit (ICU), intravenous vitamin C was associated with ...
Peanut oral immunotherapy desensitizes young children with non-anaphylactic peanut allergies
1. Compared to placebo, children who received peanut oral immunotherapy experienced significantly greater desensitization and remission. 2. Younger age at ...
Compared to prior infection, prior vaccination is associated with greater neutralization capacity against all COVID-19 variants
1. Vaccine boosters appear to be indicated for emergent SARS-CoV-2 variants in the future. 2. Although both previously infected and ...
Pertussis vaccination not linked to increase in asthma
1. This retrospective study found that children immunized against pertussis, irrespective of the form of vaccine or vaccination schedule used, ...
Donor and recipient regulatory T-cells may promote transplant tolerance in mice
1. Depletion of all Foxp3+ regulatory T-cells (Tregs) induced rejection of stable skin and heart allogeneic transplants in a hematopoietic ...
Minimal HIV adaptations to host in America over past twenty years
Image: PD HIV budding off from a lymphocyte 1. Limited HIV adaptations to host immune system and limited change in ...
Rituximab linked with reduced chronic immune disease following stem cell transplantation
Image: PD AML 1. Rituximab use is linked with a reduction in chronic graft-vs-host disease following peripheral blood stem cell ...
Lower prevalence of HPV infection in teen girls after vaccine introduction
Image: PD 1. Within 4 years of vaccine introduction, the prevalence of vaccine-type HPV strains (6,11,16,18) decreased by 56% in ...