Tag: inflammatory markers

1. Ziltivekimab lowered high-sensitivity CRP levels, a predictor of vascular events, compared to placebo in a dose-dependent manner. 2. Thrombotic biomarkers including fibrinogen, serum amyloid A, haptoglobin, secretory phospholipase A2, and lipoprotein were lower in treatment groups compared to placebo. Evidence Rating Level: 1 (Excellent) Study Rundown: Prior studies, including the landmark...
Image: PD  1. Markers of inflammation (clinical chorioamnionitis, maternal temp>38°C, histological chorioamnionitis) were all associated with adverse neonatal outcomes.  2. The association remained significant when stratified by gestational age at delivery.  Evidence Rating Level: 1 (Excellent)        Study Rundown: This study found that markers of prenatal inflammation, such as chorioamnionitis and...
Image: PD 1. Compared with pediatric burn patients who survived, those who did not had significantly higher levels of serum inflammatory markers, including IL-6, IL-8, G-CSF, and CRP.  2. Nonsurviving pediatric burn patients also had 10% greater resting energy expenditure (REE) and 40% higher cardiac output than surviving patients, indicating a...