Tag: lumasiran

1. Lumasiran was shown to decrease urinary oxalate excretion in patients with Primary Hyperoxaluria Type 1. 2. Lumasiran was shown not to cause severe or serious adverse events. Evidence Rating Level: 1 (Excellent)      Study Rundown: Oxalate is the toxic metabolite overproduced by the liver in Primary Hyperoxaluria Type 1 (PH1). The elevated...