Tag: metastatic breast cancer

Most estrogen receptor (ER)-positive breast cancers can be classified as luminal A or luminal B subtype. It has been estimated that 1 in 4 patients with ER-positive breast cancer will develop disseminated disease and experience disease-related mortality. While it has been suggested that as many as 1 in 4...
Most estrogen receptor (ER)-positive breast cancers can be classified as luminal A or luminal B subtype. It has been estimated that 1 in 4 patients with ER-positive breast cancer will develop disseminated disease and experience disease-related mortality. While it has been suggested that as many as 1 in 4...
Several late-stage cancers have been shown to acquire genomic alterations during disease evolution. In patients with breast cancer, 20% of metastatic tumors develop ESR1 mutations during endocrine therapy. However, the full spectrum of possible genomic alterations in metastatic breast cancer has not been described. In this study, the tumors...
Image: PD 1. Elevated circulating tumor cells (CTCs) prior to or following the first round of chemotherapy for metastatic breast cancer suggested a poor prognosis. 2. Early switch to alternative chemotherapy regimens did not improve progression-free or overall survival among patients with elevated CTCs. Evidence rating level: 1 (Excellent) Study rundown: Metastatic breast...