Tag: necrotizing enterocolitis

1. In a retrospective cohort study of almost 50 000 very low birth weight infants (VLBW), overall survival without major morbidity increased significantly between 2008 and 2017. 2. The largest improvements in major morbidity rates were seen for nosocomial infection (NI) and necrotizing enterocolitis (NEC), while the rates of bronchopulmonary...
1. In this multicenter, randomized controlled phase 3 study , the primary outcomes of rates of necrotizing enterocolitis, blood culture positive sepsis more than 72 hours after birth, and death before discharge did not differ significantly between preterm infants receiving probiotic B breve (BBG-001) and those receiving placebo. 2. There...
1. When comparing glycerin suppository or enemas to placebo in premature infants, there was no significant difference in terms of mortality, initiation of enteral feeding, or rectal bleeding. 2. There was a non-significant trend towards increasing rates of necrotizing enterocolitis (NEC) in infants receiving glycerin suppository or enema compared to...
1. Among very low birth weight infants with surgical necrotizing enterocolitis (NEC), those treated with anaerobic antibiotics had 0.71 times decreased odds of mortality.  2. Very low birth weight infants treated with anaerobic antibiotics had 1.71 times increased risk of developing intestinal strictures. Evidence Rating Level: 3 (Average) Study Rundown: Premature infants...
Image: PD 1. Probiotic supplementation in very preterm infants reduced the incidence of necrotizing enterocolitis (NEC), Bell Stage 2 and greater, but not late-onset sepsis or all-cause mortality.  Number needed to treat was 43 infants to prevent 1 NEC episode. 2. No adverse effects were reported with probiotic supplementation. Evidence Rating Level:...