Tag: opioid crisis

1. Cessation of opioid treatment was associated a period of increased risk of overdose or suicide, with a positive association between risk and length of treatment prior to stopping. Evidence Rating: 2 (Good) In the past decade, significant efforts have been taken in North America to mitigate opioid prescription as a means...
It is not uncommon for adolescents to inappropriately access prescription opioids from friends or family members. Recently, concerns surrounding the use of opioids that are not medically indicated, and an increased risk of initiating heroin use, have surfaced. In this prospective cohort study, 3298 high school students from Los...
1. In this case-control study in the US, opioid overdoses were associated with history of opioid prescription to a family member, with a dose-response association. 2. The association was largely driven by opioid overdoses in children. Evidence Rating Level: 3 (Average) Study Rundown: Opioid overdoses are a rising concern in North America...
1. Between 2005 and 2015, there was a small decrease in the rate of opioid prescriptions in emergency department (ED) visits to adolescents and young adults, and no change in the opioid prescribing rate in outpatient clinic visits. 2. Around half of ED visits for dental disorders, clavicle fractures, and...
1. Following clinical guidelines release, decreases were observed in the overall rate of opioid prescribing. 2. Guidelines may be associated with reduced high-dosage opioid prescriptions and the percentage of patients with overlapping benzodiazepine and opioid prescriptions. Evidence Rating Level: 2 (Good) Study Rundown: Opioid overuse and misuse remains a significant problem in...
1. Children with a history of neonatal abstinence syndrome (NAS) had higher odds of qualifying for and receiving therapies and services for educational disabilities compared to similar peers without a history of NAS. 2. Classroom therapies or services for developmental delay and speech or language impairment were significantly more common...
1. Even among healthy children using standard dosing, outpatient opioid prescriptions were associated with adverse events. 2. Older children were more likely to be prescribed outpatient opioids and to suffer adverse events related to their use. Evidence Rating Level: 2 (Good) Study Rundown: The increasing opioid epidemic among adults is well-documented in...
1. Buprenorphine and methadone maintenance treatment (MMT) was associated with reduced death in opioid users. 2. No significant associations were found between naltrexone and all-cause mortality or opioid-related mortality. Evidence Rating Level: 2 (Good) Study Rundown: Opioid overdose has become a rising problem in North America. There are several medications currently available...
1. Pediatric unintentional opioid exposures decreased by more than 75% following the introduction of child-resistant unit-dose packaging (UDP). 2. More than 20% of unintentional buprenorphine-naloxone exposures in children <6 years were associated with moderate or severe outcomes.  Study Rundown: In the past 2 decades, unintentional pediatric opioid poisonings have increased in...