1. In this case-control study in the US, opioid overdoses were associated with history of opioid prescription to a family member, with a dose-response association.
2. The association was largely driven by opioid overdoses in children.
Evidence Rating Level: 3 (Average)
Study Rundown: Opioid overdoses are a rising concern in North America...
Association Between Preoperative Opioid and Benzodiazepine Prescription Patterns and Mortality After Noncardiac Surgery
Strategies to amend clinician prescription patterns are of critical importance in addressing opioid abuse and opioid-related deaths across the United States. One potential approach involves targeting opioid-prescription practices in the perioperative period. However, little is known about...
1. In this study, the authors observed that both office-based treatments for opioid-use disorder, buprenorphine-naloxone and naltrexone, were equally clinically effective and appropriate.
2. Daily medication of buprenorphine-naloxone was found to be less costly from a healthcare sector perspective in comparison to naltrexone.
Evidence Rating Level: 2 (Good)
Study Rundown: Opioid use...