Tag: pediatrics

Neonatal seizure management – Is the timing of treatment critical? 1. In a cohort of newborn infants, treatment of seizures within an hour of seizure recognition was associated with decreased seizure burden and decreased number of total seizures over the next 24 hours.  Evidence Rating Level: 2 (Good) Seizures are a leading...

Complications following open and endovascular interventions for intermittent claudication 1. In a large cohort of patients with intermittent claudication, smoking prior to open and endovascular revascularization was associated with increased post-procedural complications. Evidence Rating Level: 2 (Good) Treatment guidelines for intermittent claudication (IC) recommend optimal medical therapy, which includes smoking cessation, prior...

1. In a randomized-controlled trial amongst infants showing early signs of autism spectrum disorder a preemptive intervention, used when atypical development first emerges, reduced the severity of symptoms and rates of diagnosis. Evidence Rating Level: 1 (Excellent) Study Rundown: Although children with autism spectrum disorder (ASD) demonstrate symptoms in earlier development,...

Comparison of Routine With Clinically Indicated Replacement of Peripheral Intravenous Catheters 1. Routine replacement of peripheral intravenous catheters (PVCs) every 96 hours was associated with fewer PVC-associated bloodstream infections (PVC-BSIs) compared to PVC replacement only when clinically indicated. Evidence Rating Level: 2 (Good) Nearly 60% of patients in hospital undergo an insertion of a...

1. 17.5% of individuals giving birth for the first time were found to have inadequate health literacy. 2. Individuals with inadequate health literacy were at greater risk themselves for C-section delivery and major peritoneal laceration, with their neonates at greater risk for being small for gestational age, having low birth...

1. In this trial, students in grades 3 to 7 who received eyeglasses through a school-based vision program achieved better reading scores and had improved academic achievement.  Evidence Rating Level: 1 (Excellent)  The number of school-age children with uncorrected visual impairment is substantial, especially in high-poverty neighbourhoods. Visual impairment has been...

Effect of screen time on recovery from concussion 1. In a single-center trial, decreased screen time during an acute concussion recovery period shortened the duration of concussive symptoms in a pediatric population.  Evidence Rating Level: 1 (Excellent)  Children and adolescents have the highest incidence of concussion, comprising many visits to the emergency...

Evidence Rating Level: 2 (Good) 1. Transdermal cannabidiol gel was found to be a safe and effective treatment for children and adolescents with developmental and epileptic encephalopathies  2. Treatment with transdermal cannabidiol was associated with a reduction in focal impaired awareness seizures and tonic-clonic seizures. Developmental and epileptics encephalopathies (DEEs)...