Tag: pediatrics

1. Seizures associated with tuberous sclerosis complex (TSC) were reduced by 30% with add-on cannabidiol treatment compared to placebo. 2. Oral cannabidiol at 25 mg/kg/day and 50 mg/kg/day were equally efficacious, although the lower dosage resulted in fewer adverse events. Evidence Rating Level: 1 (Excellent) Study rundown: Tuberous sclerosis complex (TSC) is...

1. Hyoscine butylbromide and acetaminophen have comparable and significant analgesic effects for pediatric non-specific colicky abdominal pain. Evidence Rating Level: 1 (Excellent) Cases of pediatric abdominal pain are a daily occurrence in hospital emergency wards. However, current analgesic recommendations for pediatric abdominal pain are not being adhered to, with two-thirds of...

1. A 1-year Vitamin B12 supplementation program did not improve neurodevelopment, growth, and hemoglobin levels in stunted children, compared to a placebo. Evidence Rating Level: 1 (Excellent) Vitamin B12 is necessary in numerous metabolic processes in the body. Deficiency of this vitamin in children is associated with failure to thrive, stunted...

Hyoscine butylbromide versus acetaminophen for nonspecific colicky abdominal pain in children: a randomized controlled trial 1. Hyoscine butylbromide and acetaminophen have comparable and significant analgesic effects for pediatric non-specific colicky abdominal pain. Evidence Rating Level: 1 (Excellent) Cases of pediatric abdominal pain are a daily occurrence in hospital emergency wards. However, current...

Association between neuraxial anaesthesia or general anaesthesia for lower limb revascularisation surgery in adults and clinical outcomes: population based comparative effectiveness study 1. Among patients undergoing lower limb revascularization, the use of neuraxial compared with general anesthesia was associated with decreased 30-day all-cause mortality. Evidence Rating Level: 2 (Good) Although endovascular interventions...

1. Children represented a growing percentage of total COVID-19 cases 2. Hospitalization and death remained low amongst children with COVID-19 Evidence Rating Level: 3 (Average) Study Rundown: While reported data regarding COVID-19 in adults has been robust, less resources are available regarding COVID-19 in children. This study analyzed public US State Health...

1. With 70% vaccination coverage, a 3rd trimester maternal vaccine for respiratory syncytial virus (RSV) was modelled to reduce RSV infection rates by 16.6% in infants younger than 3 months.  2. Incidence rate of RSV infections in the first 6 months of life for infants born to unvaccinated mothers was...

1. Children with congenital heart disease experience seasonal peaks (late spring and autumn) and dips (winter and summer school holidays) in physical activity. Evidence Rating Level: 1 (Excellent) Occurring in 1 of 100 live births, congenital heart disease (CHD) is the most common congenital defect in newborns. WIth survival rates increasing...

1. Among infants born ≤ 32 weeks gestational age requiring nasal continuous positive airway pressure (NCPAP), a gradual pressure wean to 3 cm H2O versus stopping at the level of approximately 5 cm H2O did not change the total number of days spent on NCPAP. Evidence Level Rating: 1 (Excellent) For...