Tag: preterm

1. The intubation-recruitment-surfactant administration-extubation procedure reduced the need for invasive ventilation in extremely preterm neonates compared to those not receiving lung recruitment. 2. There were no adverse effect on safety outcomes including in-hospital mortality, pneumothorax and intraventricular hemorrhage. Evidence Rating Level: 1 (Excellent) Study Rundown: Early surfactant administration is the most...

Surgery for Drug-Resistant Epilepsy in Children The role of surgery in cases of drug-resistant recalcitrant epilepsy in children and adolescents is currently unclear.  In this randomized control trial, 116 patients age 18 years or younger were randomized to receive neurosurgery and medical therapy or medical therapy alone to determine whether...

Amiodarone, lidocaine, or placebo in out-of-hospital cardiac arrest Anti-arrhythmic drugs are commonly used in out-of-hospital cardiac arrest for shock-refractory ventricular fibrillation. Previous studies have shown that patients who receive amiodarone are more likely to achieve a return of spontaneous circulation compared to those who are administered placebo or lidocaine. However,...

1. Preterm infants (gestational age <28 weeks) treated with inhaled budesonide within 24 hours of delivery had a significantly decreased incidence of bronchopulmonary dysplasia and mortality at 36 weeks postmenstrual age. 2. The above finding was driven by a significant decrease in the rate of bronchopulmonary dysplasia in the budesonide...

1. Women who had a term C-section in the second stage of labor were 6 times more likely to experience future preterm births than those who had a C-section in the first stage. 2. Women who had a vaginal delivery were more likely to have a future preterm birth compared...

Image: PD  1. Spontaneous delivery in early term (37-39 weeks) may be associated with subsequent spontaneous preterm labor.  2. Labor induction of term pregnancies is associated with decreased risk of subsequent spontaneous preterm birth (sPTB).  Evidence Rating Level: 2 (Good)             Study Rundown: This study showed that women who...

Image: PD 1. In a retrospective study, preterm delivery was an independent risk factor for future maternal cardiovascular-related hospitalizations.  2. The risk of maternal cardiovascular morbidity increased in a dose-dependent fashion with the number of preterm births.  Evidence Rating Level: 2 (Good)  Study Rundown: This population-based, retrospective cohort study identified a dose-dependent increase...

Image: PD 1. Even children born late preterm experienced increased odds of failing 1st grade standardized tests.  2. Reducing rates of preterm birth may be an important goal to improve elementary school academic performance. This study found that children born late pre-term were more likely to fail 1st grade standardized tests. This...

Image: PD 1. Despite advances in obstetric and neonatal care, extremely preterm or extremely low birth weight children show continued neurobehavioral impairments at age 8. 2. Impairments were noted in general intellectual ability, academic skills, and behavioral outcomes, despite corrections for socioeconomic factors and neurosensory impairment. Published today, an Australian study comparing...