Tag: SARS-CoV-2

1. Shared rooms and platoon membership within young Marine Corps recruits were risk factors for transmission of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection. 2. Most Marine Corps recruits were asymptomatic when they tested positive for the infection. Evidence Rating Level: 1 (Excellent) Study Rundown: The U.S. Department of Defense implements...
1. Patients with severe COVID-19 demonstrated a unique diaphragm myopathic phenotype compared to non-COVID-19 ICU patients. 2. It is unclear whether or not myopathy is a direct result of COVID-19. Evidence Rating Level: 2 (Good) Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has well-known respiratory implications as well as extrapulmonary manifestations. Adverse...
1. Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) was shown to spread rapidly amongst the U.S.S Theodore Roosevelt crew due to close close-quarter conditions and asymptomatic infected crew members. 2. The Navy implemented procedures prior to deployment such as 14-day quarantine and viral testing for all members to reduce the...
1. Children represented a growing percentage of total COVID-19 cases 2. Hospitalization and death remained low amongst children with COVID-19 Evidence Rating Level: 3 (Average) Study Rundown: While reported data regarding COVID-19 in adults has been robust, less resources are available regarding COVID-19 in children. This study analyzed public US State Health...
1. Children represented a growing percentage of total COVID-19 cases 2. Hospitalization and death remained low amongst children with COVID-19 Evidence Rating Level: 3 (Average) Study Rundown: While reported data regarding COVID-19 in adults has been robust, less resources are available regarding COVID-19 in children. This study analyzed public US State Health...
1. This agent-based modeling study found that a 1-week delay in implementation of social distancing requirements could have increased confirmed cases over 5-fold in urban communities such as NYC. 2. Likewise, a small decrease in adherence to guidelines resulted in a doubling of projected cases, demonstrating the importance of personal...
1. Children with MIS-C had higher titers of SARS- CoV-2 antibodies compared to patients with Kawasaki disease, COVID-19, and hospitalized controls. 2. Levels of SARS-CoV-2 antibodies correlated with higher erythrocyte sedimentation rate (ESR) and length of hospital and ICU stay Evidence Rating Level: 2 (Good) Study Rundown: Although the majority of children...
1. The standardized seroprevalence of SARS-CoV-2 antibodies in the US population was estimated to be 9.3% with significant regional variation. 2. Higher rates of seropositivity were seen in residents of non-Hispanic Black and Hispanic neighborhoods, as well as neighborhoods in the highest population density quintile. Evidence Rating Level: 3 (Average) Study...
1. Compared to standard therapy, patients in the lopinavir-ritonavir treatment group did not show reductions in 28-day mortality and progression to invasive mechanical ventilation or death. 2. There was no significant difference in length of hospital stay and proportion of patients discharged alive at 28 days for both groups. Evidence Rating...
1. Healthcare workers in patient facing roles have a 3 times greater risk of being admitted for COVID-19, compared to the general population, and their household contacts have a 2 times greater risk. 2. When examining healthcare workers in all settings, the risk between healthcare workers and the general population...