Tag: SARS-CoV-2

In a group of hospitalized COVID-19 patients, a therapeutic dose of low-molecular-weight heparin reduced major thromboembolic events and death. Evidence Rating Level: 1 (Excellent) Thrombotic events such as a deep vein thrombosis and pulmonary embolisms are common in patients hospitalized with COVID-19. Severely ill patients with COVID-19 often experience thrombosis despite...

1. Mortality rate increased from 36.9% to 51.9% from early 2020 (before May 1) to late 2020 (after May 2) for COVID-19 patients treated with ECMO. 2. Experienced centers in delivering ECMO had an almost 50% reduced mortality rate compared to inexperienced centers. Evidence Rating Level: 2 (Good) Study Rundown: ECMO (Extracorporeal...

1. An interval of 44-45 weeks between the first and second dose resulted in a four-fold increase in median antibody titers, 28-days after administration, compared to the standard interval of 8-12 weeks. 2. A two-fold increase in median IgG levels was observed among patients 28-days after receiving their third dose...

1. The proportion of patients with one or more symptom sequelae significantly decreased from 6 months (68%) to 12 months (49%). 2. 88% of patients had returned to employment within 12 months of hospital discharge. Evidence Rating Level: 2 (Good) Study Rundown: Although COVID-19-related hospitalization is common, little is known about the long-term complications among...

1. Time to recovery was lower in patients assigned to budesonide compared to usual care, meeting the superiority criteria. 2. Rate of hospitalizations or death was numerically lower in the inhaled budesonide group compared to usual care.  Evidence Rating Level: 1 (Excellent) Study Rundown: Systemic corticosteroids, such as dexamethasone, have been widely...

1. Children aged 0 to 3 years old were more likely than children aged 14 to 17 to transmit SARS-CoV-2 to other household members. Evidence Rating Level: 2 (Good) The impact of children on SARS-CoV-2 transmission during the COVID-19 pandemic is not entirely clear. In part, this is due to many household...

1. The proportion of patients with one or more symptom sequelae significantly decreased from 6 months (68%) to 12 months (49%). 2. 88% of patients had returned to employment within 12 months of hospital discharge. Evidence Rating Level: 2 (Good) Study Rundown: Although COVID-19-related hospitalization is common, little is known about the...

1. The findings of this prospective cohort study suggested poor humoral immune response following a single dose of the BNT162b2 COVID-19 vaccine in the hemodialysis patient population compared to two doses. 2. Based on the findings in this study, the second vaccine dose should not be delayed in patients receiving...

1. Risk of acute myocardial infarction and ischemic stroke was increased during the first two weeks following a COVID-19 infection compared to the general population. 2. The risk of developing acute myocardial infarction and ischemic stroke decreased in weeks 3-4 following a COVID-19 infection compared to the first two weeks. Evidence...

1. Children aged 0 to 3 years old were more likely than children aged 14 to 17 to transmit SARS-CoV-2 to other household members. Evidence Rating Level: 2 (Good) The impact of children on SARS-CoV-2 transmission during the COVID-19 pandemic is not entirely clear. In part, this is due to many...