• About
  • Masthead
  • License Content
  • Advertise
  • Submit Press Release
  • RSS/Email List
  • Write for us
  • Contact us
2 Minute Medicine
No Result
View All Result

No products in the cart.

SUBSCRIBE
  • Specialties
    • Cardiology
    • Chronic Disease
    • Dermatology
    • Emergency
    • Endocrinology
    • Gastroenterology
    • Imaging and Intervention
    • Infectious Disease
    • Nephrology
    • Neurology
    • Obstetrics
    • Oncology
    • Ophthalmology
    • Pediatrics
    • Preclinical
    • Psychiatry
    • Public Health
    • Pulmonology
    • Rheumatology
    • Surgery
  • The Scan
  • Wellness
  • Classics™
    • 2MM+ Online Access
    • Paperback and Ebook
  • Rewinds
  • Visual
  • Partners
    • License Content
    • Submit Press Release
    • Advertise with Us
  • AccountLog-in/out
    • Subscribe
    • Sign-in
    • My account
2 Minute Medicine
  • Specialties
    • Cardiology
    • Chronic Disease
    • Dermatology
    • Emergency
    • Endocrinology
    • Gastroenterology
    • Imaging and Intervention
    • Infectious Disease
    • Nephrology
    • Neurology
    • Obstetrics
    • Oncology
    • Ophthalmology
    • Pediatrics
    • Preclinical
    • Psychiatry
    • Public Health
    • Pulmonology
    • Rheumatology
    • Surgery
  • The Scan
  • Wellness
  • Classics™
    • 2MM+ Online Access
    • Paperback and Ebook
  • Rewinds
  • Visual
  • Partners
    • License Content
    • Submit Press Release
    • Advertise with Us
  • AccountLog-in/out
    • Subscribe
    • Sign-in
    • My account
SUBSCRIBE
2 Minute Medicine
Subscribe
Home All Specialties Chronic Disease

Vaccination after recovery from COVID-19 reduced rate of reinfection by half

byGursharan SohiandYuchen Dai
August 2, 2022
in Chronic Disease, COVID-19 Classics, Infectious Disease, Public Health
Reading Time: 3 mins read
0
Share on FacebookShare on Twitter

1. Completion of the primary vaccination series against COVID-19 amongst individuals who had previously recovered from the infection reduced the rate of reinfection by approximately 50% in this retrospective cohort study.

2. Patients who lived or worked in long-term care homes had higher rates of infection and reinfection than the general population.

Level of Evidence Rating: 2 (Good)

Study Rundown: Vaccination against COVID-19 is an important public health measure known to significantly reduce the rate and severity of infection. It remains possible to become reinfected with COVID after having recovered from infection, although the relationship between vaccination and reinfection risk is unclear. This study sought to describe the rate of reinfection amongst individuals who had previously recovered from COVID-19 and received protective vaccination after initial infection.

Data from a total of 100,517 individuals who had been diagnosed with COVID-19 and subsequently remained unvaccinated for 90 days was collected. During the follow-up period, 56.6% of these individuals received at least 1 dose of the vaccine. The median time between first and second COVID-19 infection for those who became reinfected was approximately 7 months. The risk of reinfection was much higher amongst unvaccinated long-term congregate care (LTCC) residents and employees compared to the unvaccinated general population. The reduction in risk of reinfection secondary to COVID-19 vaccination was approximately 50% amongst LTCC residents and staff and greater than 60% in the general population.

This retrospective cohort study reinforces the notion that vaccination against COVID-19 is an effective public health strategy for reducing the rate of infection and reinfection. This data is particularly important for high-risk individuals, including LTCC employees and residents. Strengths of this study include the large sample size and clinical utility of these findings. Limitations include the use of retrospective databases to assess reinfection rates which likely underestimates the true number of reinfections. Additionally, some misclassification bias may be introduced because the available data did not account for any vaccinations received out of state. Future research in this area should seek to determine the optimal time point for vaccination including the receipt of ‘booster’ doses to prevent reinfection in the long-term.

Click here to read this study in JAMA

RELATED REPORTS

Nirmatrelvir-ritonavir combination reduces hospitalization and mortality in COVID-19

Online cooking education may improve perceived cooking and motor competencies in children

BNT162b2 booster is safe and reduces COVID-19 transmission in older adults

Relevant reading: COVID-19 vaccination: the road ahead

In Depth [retrospective cohort]: This retrospective cohort study was conducted amongst residents of Rhode Island, USA. Statewide health surveillance data was collected between March 2020 and December 2021. Eligible participants were individuals 12 years or older who were unvaccinated at the time of COVID-19 diagnosis, and who remained unvaccinated for 90 days after initial infection. The overall cohort was divided into three categories: residents of long-term congregate care (LTCC) settings, LTCC employees and the general population.

The risk of reinfection at 9 months for unvaccinated individuals was 13% (95% confidence interval 12-14%) amongst LTCC residents, 10% (8.8-11.5%) for LTCC staff, and 1.9% (1.8-2.0%) amongst the general population. Regression analysis demonstrated that completion of COVID-19 primary vaccination series (two doses) offered 62% (95% CI, 56%-67%) protection for the general population, 49% (95% CI, 23% to 66%) for LTCC employees, and 49% (95% CI 26%-65%) for LTCC residents. Proportional hazard models further identified factors associated with modified risk of reinfection, including hospitalization for initial infection (adjusted hazard ratio [AHR] 1.91, 95% confidence interval 1.56-2.33), and White race. Male sex (0.74, 0.67-0.83) and reporting symptoms during the initial infection compared to asymptomatic individuals (0.58, 0.51-0.66) were protective against reinfection.

Image: PD

©2022 2 Minute Medicine, Inc. All rights reserved. No works may be reproduced without expressed written consent from 2 Minute Medicine, Inc. Inquire about licensing here. No article should be construed as medical advice and is not intended as such by the authors or by 2 Minute Medicine, Inc.

Tags: #COVID-19 vaccinationCOVID-19COVID-19 reinfectionlong-term care
Previous Post

#VisualAbstract: Maintenance endocrine therapy plus bevacizumab after induction with paclitaxel is effective for ER+ breast cancers

Next Post

Abrocitinib is more effective than dupilumab for treatment of moderate-to-severe atopic dermatitis

RelatedReports

Ultrasound enhances gastrointestinal absorption of drugs at low frequencies
Emergency

Nirmatrelvir-ritonavir combination reduces hospitalization and mortality in COVID-19

February 1, 2023
Eating in the absence of hunger linked to toddler obesity
Lifestyle

Online cooking education may improve perceived cooking and motor competencies in children

January 31, 2023
Social networks play key roles in parental vaccination decisions
Infectious Disease

BNT162b2 booster is safe and reduces COVID-19 transmission in older adults

January 30, 2023
Evidence-based interventions for pediatric asthma successfully adapted for community health centers
Weekly Rewinds

2 Minute Medicine Rewind January 23, 2023

January 30, 2023
Next Post
Topical pimecrolimus use for atopic dermatitis not linked to malignancy

Abrocitinib is more effective than dupilumab for treatment of moderate-to-severe atopic dermatitis

Comprehensive telehealth intervention effective for reducing HbA1c in poorly controlled diabetes

#VisualAbstract: Vitamin D supplementation does not reduce the risk of incident fractures among healthy adults

#VisualAbstract: Vitamin D supplementation does not reduce the risk of incident fractures among healthy adults

License Our Award-Winning Physician-Written Medical News and Visual Abstracts

2 Minute Medicine is the leading authoritative medical news licensing service, and the only with reports written by practicing doctors.

LICENSE CONTENT

2MM+ Premium Access

No ads & unlimited access to all current reports, over 9000 searchable archived reports, visual abstracts, Weekly Rewinds, and the online edition of The Classics Series™ textbook.

Subscription Options
2 Minute Medicine

2 Minute Medicine® is an award winning, physician-run, expert medical media company. Our content is curated, written and edited by practicing health professionals who have clinical and scientific expertise in their field of reporting. Our editorial management team is comprised of highly-trained MD physicians. Join numerous brands, companies, and hospitals who trust our licensed content.

Recent Reports

  • Cystatin C-based equation without race or sex improves accuracy of GFR estimation
  • #VisualAbstract: Aldosterone synthase inhibition reduced systolic blood pressure in patients with treatment-resistant hypertension
  • High-dose exercise therapy is not superior to low-dose exercise therapy for knee osteoarthritis
License Content
Terms of Use | Disclaimer
Cookie Policy
Privacy Statement (EU)
Disclaimer

© 2021 2 Minute Medicine, Inc. - Physician-written medical news.

  • Specialties
    • Cardiology
    • Chronic Disease
    • Dermatology
    • Emergency
    • Endocrinology
    • Gastroenterology
    • Imaging and Intervention
    • Infectious Disease
    • Nephrology
    • Neurology
    • Obstetrics
    • Oncology
    • Ophthalmology
    • Pediatrics
    • Preclinical
    • Psychiatry
    • Public Health
    • Pulmonology
    • Rheumatology
    • Surgery
  • The Scan
  • Wellness
  • Classics™
    • 2MM+ Online Access
    • Paperback and Ebook
  • Rewinds
  • Visual
  • Partners
    • License Content
    • Submit Press Release
    • Advertise with Us
  • Account
    • Subscribe
    • Sign-in
    • My account

© 2021 2 Minute Medicine, Inc. - Physician-written medical news.

Want more physician-written
medical news?

Join over 10 million yearly readers and numerous companies. For healthcare professionals
and the public.

Subscribe for free today!

Subscription options