Tag: COVID-19

1. Covid-19 case fatality estimated to be 1.6% in Canada and 1.8% in the USA Evidence Rating: 2 (Good) Covid-19 has disproportionately affected different areas of the world, not just in the number of cases, but also in the case-fatality rate (CFR): the percentage of deaths in comparison to the number...
1. Patients with haematological malignancies had poorer prognoses than patients with solid tumours, and administration of chemotherapy within 4 weeks of symptom onset was associated with higher case fatality rate. Evidence Rating: 2 (Good) Although patients with cancer have been identified as an a vulnerable population during the COVID-19 pandemic, due to...
1. SARS-CoV-2 is more transmissible in households compared to SARS-CoV and MERS-CoV. 2. Individuals aged over 60 years were the most susceptible to household transmission of SARS-CoV-2. Evidence Rating Level: 2 (Good) Study Rundown: While the transmissibility of the disease has been extensively modeled at population and individual levels, comparatively little is...
1. Non-intubated patients with COVID-19-related pneumonia had substantial, yet non-sustained, improvements in their PaO2/FiO2 ratio by over 50% after 10 minutes of prone positioning. 2. Patients who had sustained responses to prone positioning were generally prone positioned earlier and had higher inflammatory responses; however, rates of intubation between responders and...
1. Non-Hispanic black patients were shown to have higher rates of hospitalization and death from coronavirus disease 2019 (COVID-19) compared to non-Hispanic white patients in a single hospital system in Louisiana. 2. Non-Hispanic black patients did not have higher rates of in-hospital mortality compared to non-Hispanic white patients. Evidence Rating Level: 2...
Physical exercise associated with reduced risk of chronic pain in university students 1. Higher frequency, intensity, and duration of physical exercise linked to lower risk of chronic pain in Norwegian University students Evidence Rating: 3 (Average) Chronic pain is estimated to impact around one-third of the population, and is a leading cause...
1. Findings from a cohort in Bergamo, Italy indicate a roughly 30-fold increase in the incidence of Kawasaki-like disease associated with the SARS-CoV-2 outbreak. 2. Pediatric patients diagnosed with Kawasaki-like disease post COVID-19 were more likely to have a more severe form of the disease, and had higher rates of...
1. A 6-gene cluster at the locus 3p21.31 was determined to be related to Covid-19 susceptibility. 2. The ABO blood-group system was associated with disease severity, with group A facing higher risk and group O benefitting from a protective effect. Evidence Rating Level: 3 (Average) Study Rundown: Given the murky pathogenesis of...
1. Lincocin® appeared to outperform Azitro® in the treatment of pneumonia associated with Covid-19. Evidence Rating Level: 2 (Good) Although as much as 80% of patients show only minor symptoms from contracting Covid-19, complications such as pneumonia can arise from Covid-19, especially in elderly patients and individuals with chronic conditions. There...
1. Hydroxychloroquine use as post-exposure prophylaxis within 4 days of a moderate or high-risk exposure did not prevent illness compatible with Covid-19 when compared to placebo. 2. Approximately 40% of individuals taking hydroxychloroquine reported side effects, all of which were noted to be mild and GI-related. There were no serious...