Tag: COVID-19

In a group of hospitalized COVID-19 patients, a therapeutic dose of low-molecular-weight heparin reduced major thromboembolic events and death. Evidence Rating Level: 1 (Excellent) Thrombotic events such as a deep vein thrombosis and pulmonary embolisms are common in patients hospitalized with COVID-19. Severely ill patients with COVID-19 often experience thrombosis despite...
1. Immune-mediated inflammatory disease patients treated with tumor necrosis factor (TNF) inhibitor were associated with fewer hospitalizations or deaths due to COVID-19 than those treated with only methotrexate, with only azathioprine/6-mercaptopurine, with TNF inhibitor and azathioprine/6-mercaptopurine, or with only a Jak inhibitor. Evidence Rating Level: 3 (Average) Study Rundown: Treatment of...
Individuals not immune to COVID-19 had at least a 45% decreased risk of COVID-19 infection if at least one family member was immune (through previous infection or two vaccine doses). Evidence Rating Level: 2 (Good) Study Rundown: SARS-CoV-2 is predominantly transmitted through person-to-person contact, rendering the spread of this virus through...
1. In this study, higher quality diet was associated with lower risk of COVID-19. 2. Amongst participants living in areas of high socioeconomic deprivation, the association between poor diet quality and COVID-19 risk was more evident. Evidence Rating Level: 2 (Good) Patients with metabolic diseases such as obesity and Type 2 diabetes...
1. States requiring women, infants, and children program beneficiaries to either mail or present proof of beneficiary status to reload their benefits had decreased program participation during the COVID-19 pandemic. 2. Offering online benefit reloading may reduce barriers in assessing nutritional support program. Evidence Rating Level: 2 (Good) The Special Supplemental Nutrition...
Effectiveness and safety of non-steroidal anti-inflammatory drugs and opioid treatment for knee and hip osteoarthritis: Network meta-analysis 1. Topical diclofenac 70-81 mg/day was recommended as first-line pharmacological treatment for knee osteoarthritis. 2. Etoricoxib 60 mg/day and diclofenac 150 mg/day were the most effective oral NSAIDs for pain and function in OA...
2 Minute Medicine is pleased to announce that we are launching Wellness Check, a new series dedicated to exploring new research evidence focused on wellness. Each week, we will report on articles examining different aspects of wellness, including (but not limited to) nutrition, sleep, reproductive health, substance use and...
Methylprednisolone therapy in nonintubated patients with COVID-19 receiving high-flow oxygen therapy was associated with clinical benefit solely in patients with baseline serum ferritin levels in the upper tertile of values. In contrast, for patients with ferritin in the lower and middle tertiles, no association with benefit...
1. The D-dimer test threshold of 0.05 µg/mL in COVID patients had a sensitivity of 100%, a specificity of 8.8%, a negative predictive value of 100%, a positive predictive value of 13.9%, and negative likelihood ratio of <0.1 for prediction of pulmonary embolism. 2. The use of current D-dimer cutoffs...
1. In this longitudinal study of a cohort of adolescents, anxiety and depression scores increased after the COVID-19 pandemic began. 2. Male participants had higher depression scores than female participants, whereas female participants had higher anxiety scores than males. Evidence Rating Level: 3 (Average) Adolescence represents a key time period for...