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2 Minute Medicine | March 5, 2015

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2 Minute Medicine provides concise, curated, medical news written by health professionals. Keep up with the latest medical news on cardiology, infectious disease, pediatrics, internal medicine and more! Led by Harvard Physicians.

Omeprazole before endoscopy in patients with gastrointestinal bleeding [Classics Series]

March 5, 2015 |

1. Compared to placebo, treating patients with omeprazole bolus and infusion prior to endoscopy significantly reduces the need for endoscopic therapy, the rate of post-endoscopy active bleeding, and shortens hospital stays.

2. Treating patients with omeprazole pre-endoscopy did not significantly reduce the need for emergency surgery and did not reduce … Read More

Double-lung transplantation associated with lower mortality in IPF

March 3, 2015 |

1. Double-lung transplant is associated with lower 5-year mortality rates than single-lung transplant in patients with idiopathic pulmonary fibrosis (IPF).

2. There is no difference in 5-year mortality and median graft survival between single and double-lung transplants in patients with chronic obstructive pulmonary disease (COPD).

Evidence Rating Level: 2 (Good) … Read More

Continuous PPI use associated with recurrent Clostridium difficile infection

March 3, 2015 |

1. Patients on continuous proton pump inhibitor (PPI) had an increased risk of recurrence of their Clostridium difficile infection.

2. While PPI use was common, almost half of patients did not have an evidence-based indication for usage.

Evidence Rating Level: 2 (Good)

Study Rundown: Preventing recurrence of Clostridium difficile infection … Read More

Nut consumption associated with reduced overall mortality

March 3, 2015 |

1. Based on data from three different cohorts, there was about a 20% lower risk of death amongst participants who had the greatest amount of nut consumption. There was also reduced cardiovascular disease amongst these participants.

2. There was no significant difference observed regarding this positive trend between peanuts compared … Read More

2 Minute Medicine Rewind February 23 – March 1, 2015

March 3, 2015 |

In this section, we highlight the key high-impact studies, updates, and analyses published in medicine during the past week.

6- Versus 24-Month Dual Antiplatelet Therapy After Implantation of Drug-Eluting Stents in Patients Nonresistant to Aspirin: The Randomized, Multicenter ITALIC Trial

Current national society guidelines recommend 12 months of dual antiplatelet … Read More

Higher smoking rates in adult HIV population

March 2, 2015 |

1. From a cross-sectional survey, adults with HIV were associated with an increased likelihood of smoking than the general population.

2. Adults with HIV who smoke were also less likely to quit.

Evidence Rating Level: 2 (Good)       

Study Rundown: Smoking is associated with both negative health effects … Read More