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2 Minute Medicine | July 30, 2014

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Vitamin D not effective in reducing recurrent bacterial vaginosis

July 29, 2014 | Denise Pong, MPH

1. Women randomized to receive Vitamin D following treatment for bacterial vaginosis were more likely to have higher serum 25(OH)D levels. 

2. Women randomized to receive Vitamin D following treatment with metronidazole had a similar prevalence of bacterial vaginosis at 24 weeks when compared to the placebo group. 

Evidence Rating … Read More

Mutation linked with decrease in cutaneous diffuse large B-cell lymphoma

July 29, 2014 | Harrison Nguyen

1. The MYD88 mutation was associated with a shorter survival rate in primary cutaneous diffuse large B-cell lymphoma, leg type (PCLBCL-LT). 

2. The MYD88 mutation was positive in 59% of patients with PCLBCL-LT and was associated with older initial presentation and had higher likelihood of leg involvement. 

Evidence Rating Level: … Read More

Hormone therapy may not prevent atherosclerosis in menopausal women

July 28, 2014 | Sai Folmsbee

1. In this randomized, controlled trial of healthy menopausal women, hormonal therapy did not slow the progression of atherosclerosis. 

2. Depending on the hormonal therapy, there were small improvements to lipoprotein cholesterol levels and insulin resistance. 

Evidence Rating Level: 1 (Excellent) 

Study Rundown: Cardiovascular disease (CVD) is the leading cause … Read More

2 Minute Medicine Rewind July 20 – July 27, 2014

July 28, 2014 | Neal Yuan

In this section, we highlight the key high-impact studies, updates, and analyses published in medicine during the past week.

Efficacy of paracetamol for acute low-back pain: a double-blind, randomised controlled trial

Paracetamol (also known as acetaminophen) is commonly prescribed as a first-line agent for acute lower back pain, however its … Read More