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2 Minute Medicine | July 22, 2014

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2 Minute Medicine Rewind July 15 – July 21, 2014

July 21, 2014 |

In this section, we highlight the key high-impact studies, updates, and analyses published in medicine during the past week. Effects of Extended-Release Niacin with Laropiprant in High-Risk Patients Despite lack of evidence of overall benefit, niacin has been increasingly used to help lower LDL cholesterol and raise HDL cholesterol, modifiable risk factors for cardiovascular disease. [...]Read More

Weight loss intervention concurrently targeting parent and child benefits both parties

July 21, 2014 |

1. A 12-month weight loss intervention that treated overweight children and their parents concurrently produced greater initial and sustained decreases in the BMI of both parties, as compared to interventions that focused solely on the child.   2. Following completion of the intervention, parents and children in the Intervention group were better able to maintain [...]Read More

Minimal survival benefit from contralateral prophylactic mastectomy

July 21, 2014 | Maren Shapiro

1. In women with newly diagnosed breast cancer, contralateral prophylactic mastectomy conferred a minimal increase in projected life expectancy, between 1 and 7 months.  2. The survival benefit was slightly greater in younger women with stage I, ER-negative breast cancer, however the 20-year overall survival difference was still <1%.  Evidence Rating Level: 1 (Excellent)   [...]Read More

Peer-mentored therapy reduces distress in mothers of children with disabilities

July 21, 2014 | Puja Umaretiya

1. Mothers attending either peer-mentored mindfulness or positive psychology group practice had significant improvement in distress, dysfunctional parent-child interactions, anxiety, depression, insomnia, and life satisfaction during treatment; however, mothers in the mindfulness group had greater improvement in anxiety, depression, and insomnia. 2. Mothers of children with autism spectrum disorder showed decreased improvement in anxiety as [...]Read More