• About
  • Masthead
  • License Content
  • Advertise
  • Submit Press Release
  • RSS/Email List
  • Write for us
  • Contact us
2 Minute Medicine
No Result
View All Result

No products in the cart.

SUBSCRIBE
  • Specialties
    • Cardiology
    • Chronic Disease
    • Dermatology
    • Emergency
    • Endocrinology
    • Gastroenterology
    • Imaging and Intervention
    • Infectious Disease
    • Nephrology
    • Neurology
    • Obstetrics
    • Oncology
    • Ophthalmology
    • Pediatrics
    • Preclinical
    • Psychiatry
    • Public Health
    • Pulmonology
    • Rheumatology
    • Surgery
  • Wellness
  • Classics™
    • 2MM+ Online Access
    • Paperback and Ebook
  • Rewinds
  • Visual
  • Partners
    • License Content
    • Submit Press Release
    • Advertise with Us
  • AccountLog-in/out
    • Subscribe
    • Sign-in
    • My account
2 Minute Medicine
  • Specialties
    • Cardiology
    • Chronic Disease
    • Dermatology
    • Emergency
    • Endocrinology
    • Gastroenterology
    • Imaging and Intervention
    • Infectious Disease
    • Nephrology
    • Neurology
    • Obstetrics
    • Oncology
    • Ophthalmology
    • Pediatrics
    • Preclinical
    • Psychiatry
    • Public Health
    • Pulmonology
    • Rheumatology
    • Surgery
  • Wellness
  • Classics™
    • 2MM+ Online Access
    • Paperback and Ebook
  • Rewinds
  • Visual
  • Partners
    • License Content
    • Submit Press Release
    • Advertise with Us
  • AccountLog-in/out
    • Subscribe
    • Sign-in
    • My account
SUBSCRIBE
2 Minute Medicine
Subscribe
Home All Specialties Chronic Disease

2 Minute Medicine Rewind June 17- June 24

bys25qthea
June 30, 2013
in Chronic Disease, Infectious Disease, Neurology, Pulmonology, Weekly Rewinds
Reading Time: 3 mins read
0
Share on FacebookShare on Twitter

June 17 – June 24, 2013

In this section, we will highlight the some of the high-impact studies, updates, and analyses published in medicine during the past week.

Threshold-Based Insulin-Pump Interruption for Reduction of Hypoglycemia

In this multicenter open label RCT of sensor-augmented insulin pumps for patients with Type I DM and history of hypoglycemic episode, pump interruption at a threshold glucose of <70mg/dL was associated with nocturnal hypoglycemic events (P < 0.001) and fewer documented glucoses <70mg/dL. The threshold was triggered an average of 0.77 times per night, and infusion was interrupted for a median duration of 11.9 minutes. There was no difference in Hgb A1c, insulin dosages, or quality of life metrics between the two treatment and control groups. 

Rapid Blood-Pressure Lowering in Patients with Acute Intracerebral Hemorrhage

This multicenter open-label RCT compared a goal SBP <140mmHg vs. a goal SBP <180mmHg in the setting of acute intracerebral hemorrhage. In this study, there was an improvement in Rankin score (evaluation of functional status) with intensive BP treatment (pooled odds ratio for shift to higher modified Rankin score, 0.87; 95% CI, 0.77 to 1.00; P=0.04). There was no statistically significant difference in overall mortality (11.9% vs. 12.0%) or serious adverse events (23.3% vs. 23.6%), however patients in the intensive treatment arm was more likely to withdraw care (5.4% vs. 3.3%; p=0.005).

Crizotinib versus Chemotherapy in Advanced ALK-Positive Lung Cancer

RELATED REPORTS

Light exposure during sleep may alter glucose metabolism and impair cardiometabolic function

Enteric administration of recombinant human insulin to preterm infants is safe and effective

Wellness Check: Nutrition

This phase 3 open-label RCT compared 2nd line therapy (cizotinib vs. pemetrexed or doxetrexel) in patients with ALK-positive advanced NSCLC. There was a statistically significant difference in progression-free survival (7.7 months vs. 3.0 months, P < 0.001) and initial response (65% with cizotrinib vs. 29% with pemetrexed and 7% with doxetrexel), however there was no difference in overall survival (interim analysis; 20.3 months vs. 22.8 months; p=0.54).

Endosonography vs Conventional Bronchoscopy for the Diagnosis of Sarcoidosis

In this multicenter RCT, endosonography guided biopsy vs. traditional bronchoscopy and biopsy was compared for the diagnosis of pulmonary sarcoidosis. Significantly more granulomas were detected at endosonography vs bronchoscopy (114 vs 72 patients; 74% vs 48%; P < 0.001).

Seroconversion to Multiple Islet Autoantibodies and Risk of Progression to Diabetes in Children

In this prospective cohort study, investigators identified children with high genetic risk for T1DM and tracked the rate of islet autoantibody seroconversion and eventual development of T1DM. At 10 year follow-up, 69.7% of patients with multiple islet antibodies by age 15 developed T1DM vs. 14.5% of patients with single islet antibody and 0.4% of patients without islet antibodies. Progression to T1DM was faster for patients with earlier islet autoantibody seroconversion.

By David Ouyang

© 2013 2minutemedicine.com. All rights reserved. No works may be reproduced without written consent from 2minutemedicine.com. Disclaimer: We present factual information directly from peer reviewed medical journals. No post should be construed as medical advice and is not intended as such by the authors or by 2minutemedicine.com. PLEASE SEE A HEALTHCARE PROVIDER IN YOUR AREA IF YOU SEEK MEDICAL ADVICE OF ANY SORT. Content is produced in accordance with fair use copyrights solely and strictly for the purpose of teaching, news and criticism. No benefit, monetary or otherwise, is realized by any participants or the owner of this domain. 

Tags: insulinleukemiasarcoid
Previous Post

AAP policy statement addresses care of LGBTQ youth

Next Post

Preventable ED visits by top spenders are a small proportion of Medicare costs

RelatedReports

Filtered-sunlight may effectively treat neonatal jaundice in resource-poor settings
Cardiology

Light exposure during sleep may alter glucose metabolism and impair cardiometabolic function

April 19, 2022
Neonatal neuroimaging with strong negative predictive value for developmental outcomes: The NEURO study
Pediatrics

Enteric administration of recombinant human insulin to preterm infants is safe and effective

April 4, 2022
Improved glycemic control in type 1 diabetics on very low-carbohydrate diets
Wellness

Wellness Check: Nutrition

March 31, 2022
Racial, ethnic differences in outcomes of extremely preterm infants decreasing but persistent
Endocrinology

Enteral insulin reduces the duration of feeding intolerance in preterm infants

March 4, 2022
Next Post
Children still hospitalized and treated for ITP despite conservative guidelines

Preventable ED visits by top spenders are a small proportion of Medicare costs

The CORTICUS trial: Hydrocortisone in septic shock [Classics Series]

Lifestyle intervention in obese diabetics does not affect cardiovascular events

Lifestyle intervention in obese diabetics does not affect cardiovascular events

License Our Award-Winning Physician-Written Medical News and Visual Abstracts

2 Minute Medicine is the leading authoritative medical news licensing service, and the only with reports written by practicing doctors.

LICENSE CONTENT

Get 2MM+ Premium Access

No ads & unlimited access to all current reports, over 9000 searchable archived reports, visual abstracts, Weekly Rewinds, and the online edition of The Classics Series™ textbook.

Subscription Options
2 Minute Medicine

2 Minute Medicine® is an award winning, physician-run, expert medical media company. Our content is curated, written and edited by practicing health professionals who have clinical and scientific expertise in their field of reporting. Our editorial management team is comprised of highly-trained MD physicians. Join numerous brands, companies, and hospitals who trust our licensed content.

Recent Reports

  • Pelvic lymph node radiotherapy and androgen deprivation therapy augment progression-free status following prostatectomy
  • Operating the day after performing surgery the previous night not associated with adverse patient outcomes
  • Gratitude-focused writing may improve mental wellness during periods of chronic stress
License Content
Terms of Use | Disclaimer
Cookie Policy
Privacy Statement (EU)
Disclaimer

© 2021 2 Minute Medicine, Inc. - Physician-written medical news.

  • Specialties
    • Cardiology
    • Chronic Disease
    • Dermatology
    • Emergency
    • Endocrinology
    • Gastroenterology
    • Imaging and Intervention
    • Infectious Disease
    • Nephrology
    • Neurology
    • Obstetrics
    • Oncology
    • Ophthalmology
    • Pediatrics
    • Preclinical
    • Psychiatry
    • Public Health
    • Pulmonology
    • Rheumatology
    • Surgery
  • Wellness
  • Classics™
    • 2MM+ Online Access
    • Paperback and Ebook
  • Rewinds
  • Visual
  • Partners
    • License Content
    • Submit Press Release
    • Advertise with Us
  • Account
    • Subscribe
    • Sign-in
    • My account

© 2021 2 Minute Medicine, Inc. - Physician-written medical news.