Tag: insulin

1. Insulin costs steadily increased from 2006-2017. However, the out-of-pocket costs to privately insured patients remained consistent, in-part due to decreased cost-sharing. 2. Privately insured consumers with health savings accounts (HSAs) paid significantly more in out of pocket costs in comparison to those with health reimbursement arrangements (HRAs) or no-account...
1. In this randomized noninferiority trial involving newborns with asymptomatic moderate hypoglycemia, initiation of treatment at a lower blood glucose threshold resulted in no significant difference in psychomotor development at 18 months versus the traditional threshold. 2. Fewer hypoglycemic episodes occurred in the traditional threshold group, although more invasive interventions...
1. In this randomized controlled trial, patients with type 1 diabetes who used a closed-loop system spent a greater percentage of time in a target glycemic range compared to those who used a sensor-augmented insulin pump. 2. The closed-loop system was effective in reducing glycated hemoglobin level as well as...
1. In this large, longitudinal cohort study from the United States, patients with poor health status were more likely to continue insulin use compared with healthier patients. Evidence Rating Level: 2 (Good) Study Rundown: Type 2 Diabetes Mellitus (DM2) is one of the most common chronic illnesses in the world. Glycemic...
1. In this descriptive case series, 55 cases of patients with diabetes who developed Fournier gangrene while using sodium-glucose cotransporter-2 (SGLT2) inhibitors are described. 2. While neither causality nor incidence are identified in this paper, physicians prescribing SGLT2 inhibitors should be aware of the association with Fournier gangrene. Evidence Rating Level:...
Better treatments are needed for diabetic retinopathy (DR), a microvascular complication of diabetes. Intensive glycemic treatment can delay DR onset and progression, but it is unclear whether oral anti-diabetic drugs alone (OADs) or basal insulin-supported OADs are superior in terms of subsequent treatment. Traditionally, proliferative DR has been regarded...
Multiple daily injections (MDI) and continuous subcutaneous insulin infusion (CSII) are two forms of intensive insulin regimens utilized by patients with type 1 diabetes. Here, MDI and CSII are compared in terms of their safety, efficacy, and cost in the first year after a diagnosis of type 1 diabetes....
Association of Racial Disparities With Access to Kidney Transplant After the Implementation of the New Kidney Allocation System There are many reasons why a patient may be made inactive on the kidney transplant waiting list, including psychosocial or financial issues or medical comorbidities. This has important implications for a patient’s...
Induction of Labor at 41 Weeks Versus Expectant Management Until 42 Weeks (INDEX): Multicenter, Randomized Non-Inferiority Trial It has been well established that pregnancy extending beyond 42 weeks is associated with higher rates of perinatal morbidity and mortality. However, there is variability in the current management of pregnancies extending beyond...
1. In this retrospective cohort study, mean HbA1c levels decreased prior to systematic implementation of a program to switch from analogue to human insulin, after which HbA1c levels then increased slightly and remained steady. 2. Serious hypoglycemic or hyperglycemic events were not significantly different with program implementation. Evidence Rating Level: 2...