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The Classics in Medicine™: Summaries of the Landmark Trials | Search Directory

...ISBN 978-0996304283) All content © 2021 2 Minute Medicine, Inc. | Boston, MA | Main Directory Unlimited Reading for Subscribers | Need Group Access? Email info@2minutemedicine.com Use the real-time search box below to filter trials instantly by disease, drug, name, etc. (try “warfarin”) [table id=4 /]...

classics.csv

....\tAdding early metoprolol does not further decrease the risk of death post-MI compared to conventional fibrinolytic therapy alone\n2.\tUse of early metoprolol decreases the risk of reinfarction and ventricular fibrillation, but increases the risk of cardiogenic shock\n3.\tAdding clopidogrel to aspirin decreases the combined risk of death, reinfarction, or stroke post-MI, without significantly increasing the risk of major bleeding”],[“The NETT: Lu...

2 Minute Medicine Rewind December 7, 2020

...apur and surrounding areas of Kathmandu, in Nepal: These are low and middle-income communities know to have high rates of Vitamin B12 deficiency. For one year, children received 2 ug daily of a placebo or Vitamin B12 orally, with a reported 94% of doses being consumed. The primary outcomes were neurodevelopment (as measured by the Bayley-III scale), growth, and hemoglobin levels. The results did not find any significant differences in the primary...

2 Minute Medicine Rewind September 6, 2021

...as. Furthermore, as IPV is a sensitive topic, many women may not have felt comfortable or safe disclosing information regarding their domestic situation. However, the study did have many strengths including its comprehensive propensity score analyses which accounted for baseline characteristics of participants as well as risk stratification for preterm subgroups. Overall, this study highlights the importance of identifying risk factors, such as lo...

2 Minute Medicine Rewind October 12, 2020

...ing right after birth and at hospital discharge, as well as initiating skin-to-skin contact after birth. Overall, this study demonstrated the feasibility of implementing a midwifery continuity of care model for mothers at risk of PTBS, although it did not show improved outcomes compared to a standard care model.   Association between prehospital time and outcome of trauma patients in 4 Asian countries: A cross-national, multicenter cohort study 1....

2 Minute Medicine Rewind July 27, 2020

...same among all 3 groups: The adjusted mean change±SE was 3.2±5.7 for SSBs, -2.4±5.4 for ASBs, and -3.2±5.1 for USBs (p = 0.65). Body weight (p = 0.66) and fat mass (p = 0.27) were also the same. However, participants in the highest tertile of trunk fat had a significant body weight increase (p = 0.002) in the SSB group (4.4±1.0 kg) compared to ASB (0.5±0.9 kg) and USB (-0.2±0.9 kg). Finally, sweetness threshold (the concentration rated as being of...

2 Minute Medicine Rewind June 28, 2021

...was not significantly different between the PORT and observation cohorts (3-year overall survival of 78.3% and 82.8% respectively, hazards ratio 1.02, 95% CI 0.68-1.52, p = 0.93), but the locoregional recurrence-free survival rates were greater in the PORT group (66.5% versus 59.7%, HR 0.71, 95% CI 0.51-0.97, p = 0.03). No adverse events from the radiotherapy were observed. In conclusion, the use of PORT did not improve disease-free survival or ov...

2 Minute Medicine Rewind May 31, 2021

...d gynecological emergency department visits 1. Emergency department visits for common medical emergencies dropped at the start of the COVID-19 pandemic, but with no changes in complication or mortality rates from these emergencies. Evidence Rating Level: 2 (Good) Due to the COVID-19 pandemic, there were concerns that patients in medical emergencies may be hesitant to visit the hospital, potentially leading to adverse complications. For instance, s...

2 Minute Medicine Rewind August 9, 2021

...between self-reported importance of religious or spiritual beliefs and end-of-life care preferences among people receiving dialysis 1. Religious and spiritual beliefs of dialysis patients had an impact on their end-of-life care planning and resuscitation preferences. 2. An integrative approach to end-of-life care that takes into consideration patients’ religious and spiritual beliefs may be beneficial. Evidence Rating Level: 2 (Good) Patients wit...

2 Minute Medicine Rewind August 24, 2020

...ctor contributing to poorer outcomes in Indigenous patients with diabetes. For-profit long-term care homes and the risk of COVID-19 outbreaks and resident deaths 1. For-profit status of long term care homes (LTCs) were not associated with the odds of a COVID-19 outbreak. 2. For-profit status was associated with increased extent of outbreak and mortality rate. 3. Older design standards of LTCs and chain ownership were associated with poorer COVID-1...

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