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2 Minute Medicine Rewind December 7, 2020

...apur and surrounding areas of Kathmandu, in Nepal: These are low and middle-income communities know to have high rates of Vitamin B12 deficiency. For one year, children received 2 ug daily of a placebo or Vitamin B12 orally, with a reported 94% of doses being consumed. The primary outcomes were neurodevelopment (as measured by the Bayley-III scale), growth, and hemoglobin levels. The results did not find any significant differences in the primary...

2 Minute Medicine Rewind October 12, 2020

...ing right after birth and at hospital discharge, as well as initiating skin-to-skin contact after birth. Overall, this study demonstrated the feasibility of implementing a midwifery continuity of care model for mothers at risk of PTBS, although it did not show improved outcomes compared to a standard care model.   Association between prehospital time and outcome of trauma patients in 4 Asian countries: A cross-national, multicenter cohort study 1....

2 Minute Medicine Rewind June 28, 2021

...was not significantly different between the PORT and observation cohorts (3-year overall survival of 78.3% and 82.8% respectively, hazards ratio 1.02, 95% CI 0.68-1.52, p = 0.93), but the locoregional recurrence-free survival rates were greater in the PORT group (66.5% versus 59.7%, HR 0.71, 95% CI 0.51-0.97, p = 0.03). No adverse events from the radiotherapy were observed. In conclusion, the use of PORT did not improve disease-free survival or ov...

2 Minute Medicine Rewind July 27, 2020

...same among all 3 groups: The adjusted mean change±SE was 3.2±5.7 for SSBs, -2.4±5.4 for ASBs, and -3.2±5.1 for USBs (p = 0.65). Body weight (p = 0.66) and fat mass (p = 0.27) were also the same. However, participants in the highest tertile of trunk fat had a significant body weight increase (p = 0.002) in the SSB group (4.4±1.0 kg) compared to ASB (0.5±0.9 kg) and USB (-0.2±0.9 kg). Finally, sweetness threshold (the concentration rated as being of...

2 Minute Medicine Rewind May 31, 2021

...d gynecological emergency department visits 1. Emergency department visits for common medical emergencies dropped at the start of the COVID-19 pandemic, but with no changes in complication or mortality rates from these emergencies. Evidence Rating Level: 2 (Good) Due to the COVID-19 pandemic, there were concerns that patients in medical emergencies may be hesitant to visit the hospital, potentially leading to adverse complications. For instance, s...

2 Minute Medicine Rewind August 24, 2020

...ctor contributing to poorer outcomes in Indigenous patients with diabetes. For-profit long-term care homes and the risk of COVID-19 outbreaks and resident deaths 1. For-profit status of long term care homes (LTCs) were not associated with the odds of a COVID-19 outbreak. 2. For-profit status was associated with increased extent of outbreak and mortality rate. 3. Older design standards of LTCs and chain ownership were associated with poorer COVID-1...

2 Minute Medicine Rewind June 29, 2020

...fic regions, to provide a better understanding of the virulence of the SARS-CoV-2.   Prognostic value of functional capacity in different exercise protocols for heart disease 1. Prognosis of heart disease patients is associated not only with their exercise capacity, but also the type of exercise protocol used Evidence Rating: 2 (Good) Exercise testing is a common prognostic measurement used to assess heart disease patients. Exercise capacity, whic...

2 Minute Medicine Rewind August 17, 2020

...r physical activity, such as the closure of athletic facilities and shelter-in-place orders. Since past research has associated lack of physical activity to poorer mental health, there is a growing need for empirical research regarding the restrictions’ effect on physical and mental health outcomes. The aim of this study was to investigate the association between perceived alterations in physical activity (due to the restrictions) and mental healt...

2 Minute Medicine Rewind May 3, 2021

...24% of the 11-17 group and 7% of adults. Additionally, the cycle threshold for RT-PCR was lowest in adults (18.7, IQR 17.9-30.4) compared to 22.2 in the 11-17 age group (IQR 18.3-29.0, p = 0.02) and 25.1 in the under 10 age group (IQR 17.7-31.3, p < 0.001). Lower cycle thresholds indicate higher quantities of viral genetic material in the samples. As well, the median TCID50/mL was lower in the 11-17 group (316, IQR 178-2125) compared to adults (56...

2 Minute Medicine Rewind October 19, 2020

...her amounts of weekly physical exercise were associated with better carotid-to-femoral pulse wave velocities but not with carotid distensibility, which are both markers of arterial stiffness. 2. Diabetic patients may benefit from a more profound correlation between physical exercise with carotid-to-femoral pulse wave velocity. Evidence Rating Level: 2 (Good) Arterial stiffness is a risk factor for cardiovascular disease, which can be altered by ph...

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