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Classics Series, Landmark Trials in Medicine

Twin vaginal delivery as safe as cesarean [Classics Series]

...e subject to bias and confounding, researchers questioned whether Cesarean delivery truly lowered risk for adverse events. Given the increasing frequency of twin pregnancies and the public health goal to decrease Cesarean delivery and Cesarean-associated morbidity and mortality in the United States, researchers designed a large randomized controlled trial to assess whether perinatal outcomes differed by planned mode of delivery. Results demonstrat...

Operative vaginal delivery associated with higher risk of anal incontinence and pelvic organ prolapse

...n. Among women included in this study, it was found that operative vaginal delivery, vaginal delivery with the aid of forceps or a vacuum, was associated with a significantly higher risk of both anal incontinence and pelvic organ prolapse compared to spontaneous vaginal delivery. Five years following operative vaginal delivery, the cumulative incidence was highest for stress urinary incontinence followed by overactive bladder. However, 10 years fo...

The Classics in Medicine™: Summaries of the Landmark Trials | Search Directory

...ne™: Summaries of the Landmark Trials Online Edition | All Specialties The Online Edition of The Classics Series™ includes The Classics in Medicine™ textbook and all deep-dive sub-specialty books, such as The Classics in Cardiology™ , Classics in Radiology™ , etc. Over 500 landmark trial summaries included! Support the The Classics Series™ by buying the paperback or e-book editions: The Classics in Medicine™ (First Ed., ISBN 978-0996304290) The Cl...

Unexpected delivery outcomes associated with postpartum depression

...personal sense of failure or perceived disappointment from friends and family that vaginal delivery was not achieved. Click to read the study in AJOG Relevant Reading: Screening for depression during and after pregnancy Study Author, Dr. Kathryn Houston, MD, MA, talks to 2 Minute Medicine: University of California, San Francisco, Assistant Professor, Department of Obstetrics, Gynecology & Reproductive Sciences. “Women’s preferences for mode of del...

classics.csv

...ough the National Health Examination Survey\n2.\tIn multiple regression analysis, only prior history of obesity was found to be more influential than television watching on obesity prevalence”],[“The DIGAMI trial: Insulin-glucose infusion in diabetics with acute MI“,”JACC, 1995″,”1413″,”1.\tIn diabetic patients with acute myocardial infarction, insulin-glucose infusion with subsequent long-term insulin treatment reduces mortality at 1 year”],[“The...
Classics Series, Landmark Trials in Medicine

The Term Breech trial: Cesarean delivery improves perinatal outcome [Classics Series]

...ordingly, clinicians questioned whether vaginal delivery might be a similarly safe delivery mode compared to cesarean in the appropriate clinical setting. For example, in a multiparous patient in active labor with a healthy, uncompromised and appropriately sized fetus, vaginal delivery might confer an equally safe delivery for the fetus and is nearly a universally safer delivery mode for the mother compared to cesarean section. In the present work...

[Physician Comment] Long-term pelvic muscle strength reduced after vaginal childbirth, forceps delivery

...tearing occurring during pregnancy and delivery. Studies show that vaginal delivery is strongly associated with urinary incontinence and pelvic organ prolapse. Midline episiotomies and operative vaginal deliveries increase the risk of sphincter tears (in the levator ani muscle complex) and increase the risk for anal incontinence (3). However, most studies evaluating the association of childbirth with pelvic floor dysfunction have suffered from sho...

Cesarean delivery for term breech not associated with long-term benefit [Classics Series]

...ational studies demonstrated significant fetal benefit to planned cesarean delivery and subsequently a multicenter randomized controlled trial of over 2000 women, the Term Breech Trial, confirmed these findings. The landmark Term Breech Trial demonstrated a risk reduction in perinatal and neonatal death and serious neonatal morbidity during delivery and through the first 6 weeks of life. It is unclear, however, if the increased risk of adverse neo...

Cesarean delivery for term breech not associated with long-term benefit [Classics Series]

...ational studies demonstrated significant fetal benefit to planned cesarean delivery and subsequently a multicenter randomized controlled trial of over 2000 women, the Term Breech Trial, confirmed these findings. The landmark Term Breech Trial demonstrated a risk reduction in perinatal and neonatal death and serious neonatal morbidity during delivery and through the first 6 weeks of life. It is unclear, however, if the increased risk of adverse neo...

No difference between cesarean section and vaginal delivery of twins

...tween 32 and 39 weeks gestation were randomized to either planned cesarean delivery or vaginal delivery. The frequency of adverse neonatal events within 28 days of birth was 2.2% in the cesarean delivery group and 1.9% in the vaginal delivery group (P=0.49). The frequency of adverse maternal events within 28 days of birth was 7.3% in the cesarean delivery group and 8.5% in the vaginal delivery group (P=0.29). Adverse neonatal events included death...

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