Palliative care consultation linked to reduced direct hospital costs
1. In this meta-analysis of available studies, early palliative care consultation (PCC) for patients admitted to hospital with serious illness...
Sickle cell trait not linked to increased risk of ischemic stroke
1. In this meta-analysis of prospective population-based studies, sickle cell trait (SCT) was not associated with any difference in risk...
Systematic crosschecking between emergency physicians may decrease adverse events
1. In this cluster randomized crossover trial, implementation of a systematic crosschecking program between two emergency physicians significantly reduced the...
![Adverse pregnancy outcomes associated with thrombophilias [Classics Series]](https://www.2minutemedicine.com/wp-content/uploads/2015/07/Classics-2-Minute-Medicine-e1436017941513-350x250.png)
The PARADIGM-HF trial: Valsartan-neprilysin inhibitor vs. enalapril in patients with heart failure [Classic Series]
1. LCZ696, a combination of valsartan with a neprilysin inhibitor, significantly reduced the risk of death from cardiovascular causes and...
Insufficient evidence for physical activity in preventing late-life dementia
1. Physical activity interventions to prevent late-life dementia included aerobic exercise, resistance training, Tai Chi, and multidomain interventions. 2. There...
The DOSE trial: Loop diuretic strategies in acute decompensated heart failure [Classics Series]
1. The use of loop diuretics in acute decompensated heart failure is commonplace, but clinical practice varies widely with regards...
The AREDS2: No benefit from additional carotenoid and omega-3-fatty acid supplementation to original AREDS formulation [The Classics Series]
1. There was no added benefit observed with adding lutein and zeaxanthin, omega-3-fatty acids (DHA and EPA), or the combination...
The EVS: Vitrectomy results in better visual outcomes for light-perception patients [Classics Series]
1. In patients with endophthalmitis after recent lens implantation, immediate vitrectomy significantly improved visual outcomes for patients presenting with light-perception...
Canagliflozin reduces cardiovascular outcomes in patients with diabetes: The CANVAS
1. Canagliflozin, a sodium glucose cotransporter 2 (SGLT2) inhibitor, significantly reduced the risk of the primary composite outcome of cardiovascular...
The TNT trial: Intensive statin therapy in coronary heart disease [Classics Series]
1. In patients with stable coronary heart disease (CHD), high-dose atorvastatin significantly reduced the risk of major cardiovascular events when...
