![ABCD2 Score: Predicting Early Stroke Risk After Transient Ischemic Attack (TIA) [Classics Series]](https://www.2minutemedicine.com/wp-content/uploads/2013/05/web-cover-classics-with-logo-medicine-BW-small-jpg-350x250.jpg){kind=logo}
On-demand preexposure prophylaxis decreases HIV infection in high-risk men [Classics Series]
1. HIV-1 acquisition rates were significantly lower in men who used tenofovir disoproxil fumarate (TDF) and emtricitabine (FTC) preexposure prophylaxis...
![Adverse pregnancy outcomes associated with thrombophilias [Classics Series]](https://www.2minutemedicine.com/wp-content/uploads/2015/07/Classics-2-Minute-Medicine-e1436017941513-350x250.png)
The PARADIGM-HF trial: Valsartan-neprilysin inhibitor vs. enalapril in patients with heart failure [Classic Series]
1. LCZ696, a combination of valsartan with a neprilysin inhibitor, significantly reduced the risk of death from cardiovascular causes and...
Extended rivaroxaban superior to aspirin in lowering risk of recurrent venous thromboembolism: The EINSTEIN CHOICE trial
1. The EINSTEIN CHOICE trial involved patients who had a history of venous thromboembolism (VTE) and had completed 6 to...
Effective subcutaneous C1-inhibitor for hereditary angioedema prophylaxis: The COMPACT trial
1. The self-administered, subcutaneous C1-inhibitor CSL830 demonstrated a dose-dependent high efficacy in the prophylactic treatment of hereditary angioedema (HAE) attacks...
Pembrolizumab improves median survival amongst those with recurrent urothelial carcinoma
1. Patients with recurrent urothelial carcinoma experienced significantly longer median survival times when treated with pembrolizumab compared with chemotherapy agents. ...
Treating subclinical hypothyroidism and hypothyroxinemia in pregnancy does not impact child IQ
1. In pregnant women, treating subclinical hypothyroidism or hypothyroxinemia with levothyroxine did not significantly impact cognitive outcomes in children up to age...
Imatinib safe and effective as long-term treatment for chronic myeloid leukemia: The IRIS trial
1. The efficacy of imatinib in chronic phase chronic myeloid leukemia (CML) persisted after 10-year follow-up. 2. No new significant...
Tighter glucose control does not decrease ICU-free days in critically ill pediatric patients: The HALF-PINT trial
1. The study demonstrated that in critically ill pediatric patients, there was no significant difference in total number of ICU-free...
No cardiac events in patients with pacemakers or ICDs who underwent MRI: The MagnaSafe registry
1. This prospective cohort study of patients with cardiac pacemakers or implantable cardioverter-defibrillators (ICDs) undergoing magnetic resonance imaging (MRI) demonstrated no...
Periviable infants are becoming more likely to survive without neurodevelopmental impairment
1. Periviable infants born from 2008-2011 survived to 18-22 months corrected age at a higher rate than those born from...
