Intensive blood pressure lowering favored to not induce kidney disease, contrary to prior research
1. Patients managed with intensive blood pressure reduction were found to have significantly greater decreases in kidney damage biomarkers compared...
Replacement of recipient hematopoietic cells with donor cells may be a major factor in HIV remission after allo-HSCT
1. Allo-HSCT treatment resulted in significant prolonged reduction in HIV-1 viral reservoirs. 2. Mouse models showed adoptive transfer of peripheral...
ICU admissions among Medicare beneficiaries on a decade-long downward trend
1. Intensive care unit (ICU) admission rates decreased from 2006 to 2015. 2. No association was found between percentage change...
Current guidelines may not provide adequate instruction for prescribing anticoagulation in patients with atrial fibrillation
1. Significant variation in benefit per person was observed depending on stroke rates utilized in current guidelines. 2. The greatest...
Quarterly canakinumab administration associated with significantly reduced risk for gout attacks
1. Use of canakinumab was associated with reduced risk for gout attacks. 2. Canakinumab administration did not result in changes...
Tailoring fecal immunochemical tests positivity thresholds by age and sex may help to optimize colorectal cancer screening
1. Cancer detection among participants was higher with lower positivity thresholds. 2. Sensitivity with conventional fecal immunochemical tests (FIT) thresholds decreased...
Cost a key consideration of WHO guidelines for diabetes treatment intensification
1. WHO guidelines recommend selecting sulfonylureas as the single best second-line agent for Type 2 Diabetes Mellitus (T2DM) patients. 2....
Clinical guidelines may lead to better prescribing practices
1. Following clinical guidelines release, decreases were observed in the overall rate of opioid prescribing. 2. Guidelines may be associated...
One in seven U.S. adults used marijuana in 2017
1. Adults aged 18 to 34 had the highest frequency of marijuana use compared to all other age groups. 2....
E-cigarette use common, especially among younger adults and those in the LBGTQ community
1. Adults within the LBGTQ community more likely to use e-cigarettes. 2. Participants with chronic health conditions and current combustible...
