New treatment developed for cancer-induced weight loss [PreClinical]
1. In mouse models of cancer-induced fat and muscle wasting (cachexia), lower levels of the protein Ampk were accompanied...
1. In mouse models of cancer-induced fat and muscle wasting (cachexia), lower levels of the protein Ampk were accompanied...
1. Treatment with recombinant heat-shock protein 70 (rHSP70) reduced lysosomal enlargement in cells isolated from patients with various lysosomal storage...
1. A new imaging technique called differential structured illumination microendoscopy (DSIMe) was developed as a portable system that takes images...
1. PK11007, a 2-sulfonylpyrimidine molecule, was able to inhibit cell division in cancer cell lines both with and without p53...
1. Breast tissue samples from patients with BRCA1 mutations showed high expression of the protein Receptor Activator of Nuclear...
1. Fluorescent reporters for the protein Muashi (Msi) were used for live imaging in mice, and showed that cancer...
1. In several mouse models, a novel small molecule inhibitor, GNF6702 (GNF), effectively cleared infections of parasites that cause leishmaniasis,...
1. An immunotoxin was developed as a conditioning method in mice, which depleted host hematopoietic stem cells (HSCs) and allowed...
1. In multiple rodent models of type 2 diabetes, central injection of fibroblast growth factor 1 (FGF1) normalized blood...
1. The first known bifunctional inhibitor for the mechanistic target of rapamycin (mTOR) protein was developed to overcome current...
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