Teplizumab effective in maintaining β-cell function in type 1 diabetes
1. In this randomized-controlled trial, two 12-day courses of teplizumab improved C-peptide levels compared to placebo at week 78 in...
Low income associated with worse cardiovascular health in middle-aged adults
1. In this cross-sectional study, low-income middle-aged adults in the United States had increased rates of hypertension, diabetes, and cigarette...
Traffic-related air pollution is associated with increased blood pressure
1. In this randomized crossover trial, mean systolic and diastolic blood pressures were higher for unfiltered drives at one hour...
Pulsed-field noninferior to thermal ablation in treating paroxysmal atrial fibrillation
1. In this randomized noninferiority trial, pulsed-field ablation was noninferior to thermal ablation in the treatment of patients with drug-refractory...
Vancomycin and cefazolin not superior to cefazolin alone in arthroplasty prophylaxis
1. In this randomized controlled trial, the combination of vancomycin with cefazolin was not superior to surgical antimicrobial prophylaxis with...
Remote patient monitoring may improve cardiovascular outcomes in patients with hypertension
1. In this observational study, patients in high remote patient monitoring (RPM) practices had better hypertension outcomes than those at...
Gantenerumab does not slow cognitive decline in early Alzheimer’s
1. In these two randomized parallel-group trials, the use of gantenerumab did not lead to slower cognitive decline over 116...
Botulinum toxin effective in treating isolated or essential head tremor
1. In this randomized controlled trial, botulinum toxin was more effective than placebo in treating isolated or essential head tremor...
Ceftobiprole non-inferior to daptomycin in treating Staphylococcus aureus bacteremia
1. In this randomized controlled trial, treatment of patients with complicated Staphylococcus aureus (S. aureus) bacteremia with ceftobiprole was non-inferior...
Sarilumab increases remission rate in patients with polymyalgia rheumatica relapse
1. In this randomized controlled trial, patients with polymyalgia rheumatica (PMR) flares who received sarilumab with a prednisone taper demonstrated...