Oxaliplatin non-inferior to cisplatin for gastric cancer treatment
1. Oxaliplatin plus S-1 was non-inferior in terms of overall survival and progression free survival when compared to cisplatin plus...
Low dose CT screening may detect early lung cancers: the NELSON trial
1. In a high-risk population, low-dose CT screening detected lung cancer with 84.6% sensitivity and 98.6% specificity. 2. Screen-detected cancers...
Clinically undetectable ovarian and tubal tumors may be present in high-risk patients
1. A non-randomized control trial of 996 women at high risk for developing ovarian and tubal cancer found that 2.6%...
Proton radiotherapy may be effective for refractory pituitary adenomas
1. Treatment of refractory functional pituitary adenomas with stereotactic proton beam therapy was associated with a high rate of local...
New method may predict response to chemotherapy for lung cancer
1. In a microarray analysis of excised lung tumor specimens, 12 miRNAs were found to be associated with response to...
Bevacizumab with induction and neoadjuvant chemoradiation may be effective in rectal cancer
1. In a phase II trial of T3 resectable rectal cancer, adding bevacizumab to induction and neoadjuvant chemoradiation resulted in...
High post-surgery vitamin D levels linked with increased survival in colon cancer
1. In patients with Stage I-III colorectal cancer, higher postoperative serum 25-hydroxy vitamin D levels were associated with decreased cancer-specific...
Novel aromatase inhibitor, ODM-201, may be safe and effective for prostate cancer
1. In a phase I trial, ODM-201 was well tolerated up to 1800mg per day in prostate cancer patients, without...
Trastuzumab associated with increased reversible cardiac changes
Image: PD 1. At 8 years median follow-up, trastuzumab treatment for HER2-positive breast cancer is associated with slightly increased rates...
Captopril mitigates radiation-induced lung fibrosis in rats
Image: PD 1. Captopril or the synthetic antioxidant, EUK-207, reduced functional, biochemical, and histopathological signs of lung fibrosis after whole...