Radiofrequency denervation not effective in chronic low back pain
1. This series of multi-center, non-blinded randomized control trials found that there was either no improvement or no clinically important...
Lower rates of hypoglycemia in patients treated with insulin degludec
1. Treatment with insulin degludec resulted in a lower rate of overall symptomatic hypoglycemic episodes compared with insulin glargine U100....
Cetuximab and bevacizumab are similar in combined platin therapy for advanced or metastatic colorectal cancer
1. In this randomized controlled trial, cetuximab or bevacizumab combined with platin therapy had similar survival rates for patients with...
![Adverse pregnancy outcomes associated with thrombophilias [Classics Series]](https://www.2minutemedicine.com/wp-content/uploads/2015/07/Classics-2-Minute-Medicine-e1436017941513-350x250.png)
The SHIFT: Ivabradine in congestive heart failure [Classics Series]
1. In patients with congestive heart failure (CHF) and baseline heart rate >70 bpm, ivabradine significantly reduced the risk of...
Universal testing and treatment of HIV in East Africa led to improved coverage with antiretroviral therapy and improved viral suppression
1. This cluster randomized control trial found that implementing community-based testing and treatment program in East Rural Africa significantly increased...
Intra-articular corticosteroids unlikely to benefit osteoarthritis patients
1. In this double blind, randomized controlled trial, intra-articular triamcinolone injections did not prevent cartilage degeneration compared to saline injection...
No beneficial effects of oral iron repletion in patients with heart failure and iron deficiency
1. Oral iron repletion did not improve exercise capacity as measured by peak oxygen uptake (VO2). 2. There were no...
Academic medical center detailing policies impact physician prescribing
1. Implementation of detailing policies at academic medical centers led to modest but significant changes in prescribing behavior by physicians...
Current trends in financial relationships between industry and physicians
1. In this 2015 US-based, retrospective study, half of physicians received payments from industry. 2. Surgeons had the highest likelihood...
Antidepressant use in pregnancy not linked with autism-spectrum disorder in exposed children
1. No significant association between serotonergic antidepressant use and autism spectrum disorder risk was found between exposed and unexposed children....
