Outreach efforts improve rates of colon cancer screening
1. This randomized clinical trial showed that among persons aged 50-64 years, mailed outreach invitations offering either fecal immunochemical tests...
Physician notification increases patient participation in colorectal cancer screening
1. Providing physicians with a list of patients requiring colorectal cancer screening results in a small but significant increase in...
NT-proBNP guided therapy non-superior for heart failure with reduced ejection fraction
1. In this multicenter, randomized controlled study, the use of NT-proBNP levels to guide medical interventions for heart failure with...
Levosimendan not effective in reducing postoperative low cardiac output syndrome in select heart surgery patients
1. Compared with placebo, levosimendan did not reduce the need for prolonged catecholamine infusion, use of left ventricular assist device,...
Cerebral embolic protection devices not effective in surgical aortic valve repair
1. This randomized clinical trial showed that cerebral embolic protection devices did not significantly reduce the risk of CNS infarction...
First-line use of contact aspiration not superior to stent retriever for acute ischemic stroke
1. In patients presenting with acute ischemic stroke, first-line use of contact aspiration was not found to result in an...
Despite adverse events, corticosteroids may benefit patients with IgA nephropathy
1. In this multicenter, double blind study, IgA nephropathy patients had improved kidney function with corticosteroid treatment compared to those...
Genetic variants related to serum calcium levels associated with coronary artery disease
1. This Mendelian randomized study found that a genetic predisposition to higher serum calcium levels was associated with an increased...
Increased neurodegenerative pathology associated with chronic traumatic encephalopathy severity
1. In this retrospective study of post-mortem tissue from former American football players, pathological markers of neurodegeneration were frequent in...
![Adverse pregnancy outcomes associated with thrombophilias [Classics Series]](https://www.2minutemedicine.com/wp-content/uploads/2015/07/Classics-2-Minute-Medicine-e1436017941513-350x250.png)
The TNT trial: Intensive statin therapy in coronary heart disease [Classics Series]
1. In patients with stable coronary heart disease (CHD), high-dose atorvastatin significantly reduced the risk of major cardiovascular events when...