No therapies for computer vision syndrome with high certainty evidence in meta-analysis
1. A systematic review and meta-analysis of 45 randomized controlled trials on the treatment of computer vision syndrome (CVS) found...
Monthly brolucizumab is noninferior to aflibercept in treating recalcitrant wet age-related macular degeneration
1. In a phase 3a randomized trial comparing intravitreal brolucizumab to aflibercept for refractory neovascular age-related macular degeneration (nAMD), there...
High pediatric sequential organ failure assessment (pSOFA) score may predict hospital mortality in emergency department setting
1. In a large cohort study, children presenting to emergency departments with a score of 2 or higher on the...
Serum lipid levels are positively associated with intraocular pressure
1. In a cohort of 100,000 patients, increased levels of total cholesterol, high-density lipoprotein (HDL) cholesterol, and low-density lipoprotein (LDL)...
Preterm birth associated with differences in optic disc morphology in adulthood
1. In a cohort of approximately 750 eyes of 400 adults, vertical cup-to-disc ratio (VCDR) was significantly increased for individuals...
Noninvasive ventilation with neurally adjusted ventilatory assist (NIV-NAVA) outperforms nasal continuous positive airway pressure (NCPAP) post-extubation in preterm infants
1. In a randomized controlled trial of 70 infants born before 30 weeks’ gestation, rates of extubation failure within 72...
Antenatal corticosteroids may affect neurodevelopment differently based on gestational age
1. In a systematic review and meta-analysis of 30 cohort studies, antenatal corticosteroid use was associated with significantly decreased rates...
Exposure to hydraulic fracturing sites is associated with some adverse birth outcomes
1. In a large cohort comparing 35,000 pregnancies of women living near hydraulic fracturing sites to unexposed controls in rural...
Rapid genotyping for variant associated with aminoglycoside-induced ototoxicity is feasible in acute neonatal setting
1. In a prospective implementation trial, more than 400 infants were tested for the MT-RNR1 m.1555A>G variant using a point-of-care...
Very low birth weight associated with brain volume differences in adulthood
1. In a cohort of about 80 adults who were born with very low birth weight (VLBW), total brain volume...
