• About
  • Masthead
  • License Content
  • Advertise
  • Submit Press Release
  • RSS/Email List
  • Write for us
  • Contact us
2 Minute Medicine
No Result
View All Result

No products in the cart.

SUBSCRIBE
  • Specialties
    • Cardiology
    • Chronic Disease
    • Dermatology
    • Emergency
    • Endocrinology
    • Gastroenterology
    • Imaging and Intervention
    • Infectious Disease
    • Nephrology
    • Neurology
    • Obstetrics
    • Oncology
    • Ophthalmology
    • Pediatrics
    • Preclinical
    • Psychiatry
    • Public Health
    • Pulmonology
    • Rheumatology
    • Surgery
  • The Scan
  • Wellness
  • Classics™
    • 2MM+ Online Access
    • Paperback and Ebook
  • Rewinds
  • Visual
  • Partners
    • License Content
    • Submit Press Release
    • Advertise with Us
  • AccountLog-in/out
    • Subscribe
    • Sign-in
    • My account
2 Minute Medicine
  • Specialties
    • Cardiology
    • Chronic Disease
    • Dermatology
    • Emergency
    • Endocrinology
    • Gastroenterology
    • Imaging and Intervention
    • Infectious Disease
    • Nephrology
    • Neurology
    • Obstetrics
    • Oncology
    • Ophthalmology
    • Pediatrics
    • Preclinical
    • Psychiatry
    • Public Health
    • Pulmonology
    • Rheumatology
    • Surgery
  • The Scan
  • Wellness
  • Classics™
    • 2MM+ Online Access
    • Paperback and Ebook
  • Rewinds
  • Visual
  • Partners
    • License Content
    • Submit Press Release
    • Advertise with Us
  • AccountLog-in/out
    • Subscribe
    • Sign-in
    • My account
SUBSCRIBE
2 Minute Medicine
Subscribe
Home All Specialties Obstetrics

Bariatric surgery before pregnancy linked to lower risk of gestational diabetes

byJon LiuandMatthew Growdon
February 26, 2015
in Obstetrics, Pediatrics, Surgery
Reading Time: 3 mins read
0
Share on FacebookShare on Twitter

1. Bariatric surgery in obese patients before pregnancy was associated with a lower incidence gestational diabetes, large-for-gestational infants, and macrosomia.

2. The incidence of stillbirth and neonatal death was slightly higher in mothers who underwent bariatric surgery; however, this was of only borderline statistical significance.

Evidence Rating Level: 2 (Good)

Study Rundown: Obesity is defined as having a body-mass index (BMI) of greater than 30 kg/m2. While obesity is commonly linked to cardiovascular comorbidities, obesity during pregnancy is a key risk factor for the development of gestational diabetes and subsequent complications such as macrosomia, complications at delivery, and an increased risk of future type 2 diabetes. Prior small studies have shown that bariatric surgery prior to conception may have benefits in terms of reducing pregnancy risks to both mother and fetus.

Using a national Swedish registry, this retrospective cohort study first identified obese women who underwent bariatric surgery and then found similar obese pregnant women who did not undergo bariatric surgery. The groups were well matched for maternal age, BMI, smoking status, educational level and nulliparity.

Compared to matched controls, those with pre-pregnancy bariatric surgery had a statistically significantly lower incidence of the following: gestational diabetes, large-for-gestational infant, and macrosomia. However, bariatric surgery increased the risk of infants being small for gestational age. The incidence of stillbirth or neonatal death was higher in the bariatric surgery group; however, this was only of borderline statistical significance.

This study garners strength from the large size of the cohorts under consideration. The database used for the study involved mostly Caucasians from Sweden; therefore, results cannot be generalized to other ethnicities. While the bariatric-surgery cohort was well matched to the control cohort based on a number of key potential confounding factors, other important yet unaccounted characteristics between the matched groups may have been missed. Future studies will be required to better understand the finding of increased incidence of stillbirths and neonatal death in the bariatric surgery group (which reached marginal significance).

RELATED REPORTS

2 Minute Medicine Rewind January 23, 2023

Weekly semaglutide associated with reduced BMI in adolescents with obesity

Fecal microbiota transplantation not associated with weight loss in bariatric surgery patients

Click to read the study, published today in NEJM

Click to read an accompanying editorial in NEJM

Relevant Reading: Obesity in Pregnancy (Committee Opinion) – The American College of Obstetricians and Gynecologists

In-Depth [retrospective cohort]: This nationwide Swedish cohort study retrospectively examined the incidence of gestational diabetes and other perinatal outcomes from two matched cohorts (from 2006-2011): bariatric surgery for obese women before pregnancy (median 1.8 years prior to pregnancy) and no bariatric surgery for obese women before pregnancy. Up to five control pregnancies (without bariatric surgery) were matched to the bariatric surgery cases. Matched data involved 596 births to 554 mothers after bariatric surgery and 2,356 matched control births to 2,278 mothers without bariatric surgery. The two groups were well matched for maternal age, smoking status and educational level. Mean body-mass index and the baseline incidence of certain comorbidities (respiratory disease, psychiatric disease and substance abuse) were higher in the bariatric surgery groups (p<0.001 for all).

Patients undergoing bariatric surgery before pregnancy were less likely to develop gestational diabetes (OR 0.25, p<0.001) or to have large-for-gestational age infants (OR 0.33, p<0.001). However, the risk of small-for-gestational age infants was higher in the bariatric surgery group (OR 2.20, p<0.001), as was the risk of stillbirth or neonatal death (1.7% in the bariatric surgery group versus 0.7% in the non-bariatric surgery group, OR 2.39, p=0.06). There was no difference between the two groups in terms of major congenital malformations (OR 0.72, p=0.27) or low birth weight infants (OR 1.34, p=0.17).

Image: CC/Nancy Price

©2015 2 Minute Medicine, Inc. All rights reserved. No works may be reproduced without expressed written consent from 2 Minute Medicine, Inc. Inquire about licensing here. No article should be construed as medical advice and is not intended as such by the authors or by 2 Minute Medicine, Inc.

Tags: bariatric surgeryobesity
Previous Post

Bionic hand reconstruction shows initial promise in brachial plexus injuries

Next Post

The HAPO trial: hyperglycemia and adverse pregnancy outcomes [Classics Series]

RelatedReports

Many new pediatric asthma cases attributable to obesity
Weekly Rewinds

2 Minute Medicine Rewind January 23, 2023

January 23, 2023
Nearly Half of All Pediatric Buprenorphine Exposures Result in Hospitalization
Chronic Disease

Weekly semaglutide associated with reduced BMI in adolescents with obesity

December 26, 2022
Many new pediatric asthma cases attributable to obesity
Chronic Disease

Fecal microbiota transplantation not associated with weight loss in bariatric surgery patients

December 22, 2022
Admission may not be needed following sleep apnea surgery
Chronic Disease

Bariatric surgery may provide benefit in treating obstructive sleep apnea

November 22, 2022
Next Post
Classics Series, Landmark Trials in Medicine

The HAPO trial: hyperglycemia and adverse pregnancy outcomes [Classics Series]

Spironolactone not beneficial in heart failure with preserved ejection fraction [TOPCAT trial]

Peptides mimicking cardiac receptors combat autoimmune-mediated heart failure [PreClinical]

Flexible sigmoidoscopy decreases colorectal cancer incidence and mortality

Active smoking may increase mortality among colorectal cancer survivors

License Our Award-Winning Physician-Written Medical News and Visual Abstracts

2 Minute Medicine is the leading authoritative medical news licensing service, and the only with reports written by practicing doctors.

LICENSE CONTENT

2MM+ Premium Access

No ads & unlimited access to all current reports, over 9000 searchable archived reports, visual abstracts, Weekly Rewinds, and the online edition of The Classics Series™ textbook.

Subscription Options
2 Minute Medicine

2 Minute Medicine® is an award winning, physician-run, expert medical media company. Our content is curated, written and edited by practicing health professionals who have clinical and scientific expertise in their field of reporting. Our editorial management team is comprised of highly-trained MD physicians. Join numerous brands, companies, and hospitals who trust our licensed content.

Recent Reports

  • Chronic obstructive pulmonary disease associated with worse postoperative outcomes
  • Empagliflozin use is associated with slower progression of chronic kidney disease
  • Diagnostic tool may help identify cerebral palsy regardless of encephalopathy features
License Content
Terms of Use | Disclaimer
Cookie Policy
Privacy Statement (EU)
Disclaimer

© 2021 2 Minute Medicine, Inc. - Physician-written medical news.

  • Specialties
    • Cardiology
    • Chronic Disease
    • Dermatology
    • Emergency
    • Endocrinology
    • Gastroenterology
    • Imaging and Intervention
    • Infectious Disease
    • Nephrology
    • Neurology
    • Obstetrics
    • Oncology
    • Ophthalmology
    • Pediatrics
    • Preclinical
    • Psychiatry
    • Public Health
    • Pulmonology
    • Rheumatology
    • Surgery
  • The Scan
  • Wellness
  • Classics™
    • 2MM+ Online Access
    • Paperback and Ebook
  • Rewinds
  • Visual
  • Partners
    • License Content
    • Submit Press Release
    • Advertise with Us
  • Account
    • Subscribe
    • Sign-in
    • My account

© 2021 2 Minute Medicine, Inc. - Physician-written medical news.

Want more physician-written
medical news?

Join over 10 million yearly readers and numerous companies. For healthcare professionals
and the public.

Subscribe for free today!

Subscription options