Dolutegravir-containing antiretroviral regimens show effective viral suppression in pregnant women with HIV-1 infections

1. Dolutegravir-based antiretroviral therapy regimens effectively suppressed maternal viral load during pregnancy, supporting their use to prevent vertical transmission. 2. Dolutegravir, emtricitabine, and tenofovir alafenamide...

Quality improvement initiative increases rates of evidence-based ventilation strategy in NICU

 1. In this single center quality improvement study, the use of any volume-targeted ventilation in premature infants increased by 16%, and exclusively volume-targeted ventilation increased...

Effect of high-frequency spinal cord stimulation in patients with painful diabetic neuropathy

1. Pain relief and health-related quality of life was significantly improved among those undergoing 10-kHz spinal cord stimulation, compared to conventional medical management. 2. Outcomes...

Southern and Northern Africa continue to be disproportionately affected during the second wave of...

1. Analysis of the two distinct waves of the COVID-19 pandemic in Africa showed a more severe second wave with less stringent public health...

Association of preterm birth with long-term risk of heart failure into adulthood

1. Pre-term birth was associated with significantly increased risk of adult-onset heart failure, particularly among those 18 to 43 years of age. Evidence Rating Level:...

Post-COVID Syndrome is linked to higher mortality risk and multi-organ dysfunction

1. Hospital readmission and mortality rates were higher in post-COVID patients as compared to matched control groups. 2. More diagnoses of respiratory disease, diabetes, and...

Edema index predicts cardiorespiratory fitness in patients with HFrEF and type 2 diabetes mellitus

1. Bioelectric impedance analysis-measured edema index (EI) is a feasible, non-invasive technique for measuring fluid overload. 2. EI is an independent predictor of cardiorespiratory fitness...

Postponing renal replacement therapy may result in poor clinical outcomes in patients with severe...

1. The median number of RRT-free days was 12 days (IQR 0-25) in the delayed strategy and 10 days (IQR 0-24) in the more-delayed...

Aprepitant regimen is linked to decreased chemotherapy-induced nausea and vomiting in women

1. Aprepitant in conjunction with palonosetron and dexamethasone is associated with increased antiemetic efficacy during FOLFOX or FOLFIRI chemotherapy in women Evidence Rating Level: 1...

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