Quick Take: Body composition and cardiovascular events in patients with colorectal cancer
Patients with colorectal cancer (CRC) are 2-4 times more likely to develop cardiovascular disease, as compared to individuals without a history of cancer. With...
Lipid profiles of US youth improving over last two decades
1. In this serial, cross-sectional analysis, US youths had improved triglycerides, LDL, HDL, and total cholesterol from 1999 to 2016.2. While half of all...
Early myocardial infarction and familial hypercholesterolemia
1. In this retrospective cohort study of adults under age 50 with myocardial infarction, 9% met criteria for definite or probable familial hypercholesterolemia, which...
Use of aspirin for primary prevention linked to increased risk of intracranial hemorrhage
1. In this systematic review and meta-analysis, use of low-dose aspirin in patients without symptomatic cardiovascular disease was linked with an increased risk of...
Unrecognized obstructive sleep apnea increases risk of postoperative cardiovascular events
1. In this prospective cohort study, severe but not moderate, unrecognized obstructive sleep apnea was associated with increased postoperative cardiovascular events in patients undergoing...
The EXTEND trial: neurological deficits decreased with thrombolysis up to 9 hours after stroke...
1. Patients presenting between 4.5 and 9 hours after stroke onset with viable brain tissue who received thrombolytic therapy had better neurological outcomes compared...
Cardiovascular outcomes of dialysis patients using phosphate binders with or without calcium
1. In this observational cohort study of patients with end-stage renal disease (ESRD) undergoing hemodialysis, there was no observed difference in cardiovascular events for...
Mavacamten shows promise for treating patients with obstructive hypertrophic cardiomyopathy
1. In this open-label clinical trial, mavacamten was found to reduce mean postexercise left ventricular outflow tract gradient after 12 weeks of treatment, which...
Patent foramen ovale associated with four-fold increased risk for ischemic stroke in patients with...
1. In this prospective cohort study, patients with symptomatic pulmonary embolism (PE) and a patent foramen ovale (PFO) were found to have a significantly...
Ticagrelor reversal agent provides immediate and sustained effect
1. A monoclonal antibody fragment to ticagrelor, PB2452, increased platelet function significantly in healthy patients given the oral P2Y12 inhibitor ticagrelor.2. Adverse effects were...
