Supraglottic airway resuscitation likely more or just as effective as endotracheal intubation for out-of-hospital...
1. In an American, randomized controlled trial, supraglottic airway (SGA) resuscitation was associated with marginally better neurological outcomes and 72-hour survival compared to endotracheal...
Improved cardiovascular health associated with lower incidence of dementia in older adults
1. In this prospective cohort study, older patients with more optimal cardiovascular (CV) health metrics had a lower rate of developing dementia in a...
Optimization of cardiovascular health metrics associated with better cerebrovascular structure and function in young...
1. In this cross-sectional study, young adults with a greater number of modifiable cardiovascular (CV) risk factors at recommended levels was associated with higher...
Triple combination antihypertension therapy improves blood pressure control for mild-to-moderate hypertension
1. In this randomized controlled trial, patients receiving triple combination antihypertension therapy (TCAT) were more likely to achieve their blood pressure target compared to...
Microtubules linked to cardiomyocyte function in heart failure [PreClinical]
1. Post-translational detyrosination of microtubules results in resistance to cardiomyocyte sarcomere shortening and stretch.
2. Pharmacologic and genetic strategies to inhibit the detyrosination of...
Idiopathic inflammatory myositis linked to statin exposure
1. In this case control study from Australia, patients with histologically confirmed idiopathic inflammatory myositis (IIM) were more likely to report exposure to statin...
Fewer adverse myocardial events in depressed patients treated with antidepressants after acute coronary syndrome
1. In this prospective cohort study, depressed patients with Acute Coronary Syndrome (ACS) who were treated with escitalopram were less likely to have Major...
Patisiran is effective in treatment of hereditary transthyretin amyloidosis.
1. Patisiran, an RNA interference agent, improved neuropathy symptoms and motor function in patients with hereditary transthyretin amyloidosis after 18 months of use.
2. Types...
Alteplase unlikely to reduce disability after mild stroke without disabling deficits
1. In this randomized controlled trial, administration of alteplase within 3 hours of mild stoke did not lead to a reduction in disability at...
Active EKG monitoring screening leads to earlier diagnosis and treatment for atrial fibrillation compared...
1. In this randomized controlled trial, patients who received immediate atrial fibrillation (AF) monitoring with a new, wearable EKG were more likely to have...
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