![Novel biodegradable sirolimus-eluting stents non-inferior to durable everolimus-eluting stents [BIOSCIENCE trial]](https://www.2minutemedicine.com/wp-content/uploads/2014/09/Taxus_stent_FDA-e1607803635904-350x250.jpg)
Paclitaxel-coated devices do not reduce rates of major amputations in chronic limb-threatening ischemia
1. All-cause mortality and reduction in major amputations were similar between groups. 2. The rate of target vessel reintervention was...
Chronic Disease
Reports of high-impact chronic disease studies by medical professionals
Effect of Intensive Blood Pressure Lowering Treatment on Retinal Microvasculature: Secondary Analysis From ESPRIT
1. Intensive systolic blood pressure (SBP) management reduces hypertension-mediated retinal microvascular damage in populations with high cardiovascular risk Evidence Rating...
Clopidogrel monotherapy is superior to aspirin for secondary prevention in coronary artery disease
1. Major adverse cardiovascular and cerebrovascular events were significantly reduced with clopidogrel compared to aspirin alone. 2. There was no...
Influenza vaccination improves survival and reduces readmissions in patients hospitalized for acute heart failure
1. All-cause mortality and hospital readmissions were significantly decreased with influenza vaccination compared to usual care. 2. Significantly fewer adverse...
Endoscopic sinus surgery improves quality of life compared with clarithromycin and placebo in chronic rhinosinusitis
1. Patients in the endoscopic sinus surgery group reported lower SNOT-22 scores at 6 months, suggesting improved quality-of-life metrics. 2....
![2 Minute Medicine: Pharma Roundup: Price Hikes, Breakthrough Approvals, Legal Showdowns, Biotech Expansion, and Europe’s Pricing Debate [May 12nd, 2025]](https://www.2minutemedicine.com/wp-content/uploads/2025/05/ChatGPT-Image-May-12-2025-at-10_22_23-AM-350x250.png)
2 Minute Medicine: Pharma Roundup – Breakthrough ALS gene therapy, new adult pneumonia vaccine, needle-free obesity treatment, and Pfizer’s business overhaul [October 28, 2025]
Amryta’s Sodesta gene therapy gains accelerated approval for ALS The Food and Drug Administration has granted accelerated approval to Sodesta,...
Gut inflammation is associated with structural spinal damage in axial spondyloarthritis – results from the observational SPARTAKUS cohort
1. Increased gut inflammation, as measured by fecal calprotectin, is significantly associated with greater structural spinal damage in axial spondyloarthritis...
Exposure to components of fine particulate matter is associated with risk of autism spectrum disorder
1. In this cohort of singleton births in Ontario, prenatal exposure to specific components of Fine particulate matter (PM2.5), specifically...
Glucose-Lowering Medication Classes and Cardiovascular Outcomes in Patients With Type 2 Diabetes
1. In patients with type 2 diabetes (T2D), the risk of major adverse cardiovascular events (MACEs) was lowest among patients...
Smartphone-Based Muscle Relaxation for Migraine in the Emergency Department
1. Among adults presenting to the emergency department (ED) with migraine, a smartphone-based progressive muscle relaxation (PMR) program significantly reduced...
